Table 3

Correlations of blood lead with heart rate variability measured by Fourier transform

VariableUnadjustedAdjusted
Estimate (95% CI)P valueEstimate (95% CI)P value
Supine position
 Total power (%)23.3 (–9.6 to 68.7)0.193.0 (–20.4 to 33.0)0.82
  Low-frequency power (nu)–3.00 (–7.83 to 1.83)0.22–2.26 (–7.09 to 2.57)0.36
  High-frequency power (nu)–1.59 (–5.24 to 2.06)0.39–2.60 (–6.01 to 0.81)0.13
  Low to high frequency ratio (%)–1.8 (–20.8 to 21.6)0.876.2(–12.9 to 29.1)0.56
Standing position
  Total power (%)11.7 (–17.0 to 50.3)0.46–6.0 (–26.2 to 19.7)0.61
  Low-frequency power (nu)–1.037 (–6.22 to 4.14)0.69–1.36 (–6.48 to 3.76)0.60
  High-frequency power (nu)–1.61 (–3.78 to 0.55)0.14–1.66 (–3.79 to 0.47)0.13
  Low to high frequency ratio (%)14.0 (–7.3 to 40.3)0.21–14.0 (–4.9 to 42.2)0.14
Orthostatic change
  Total power (%)–8.8 (–31.8 to 17.5)0.47–8.8 (–31.8 to 17.5)0.47
  Low-frequency power (%)4.7 (–6.7 to 20.2)0.42–2.3 (–8.8 to 17.4)0.74
  High-frequency power (%)–8.8 (–27.6 to 14.8)0.40–6.7 (–24.2 to 14.8)0.61
  Low to high frequency ratio (%)14.8 (–8.8 to 47.9)0.227.2 (–14.9 to 34.9)0.52
  • Covariables in adjusted models included age, heart rate (or heart rate change for orthostatic changes), mean arterial pressure and serum insulin. Association sizes, given with 95% CI, are the difference in the outcome variable associated with a 10-fold increase in the blood lead concentration. For logarithmically transformed outcomes, differences are given as a percentage or as a percentage change on assuming the standing from the supine position.