Date of birth | Before 08.05.1929 (early birth cohorts) | After 08.05.1929 (late birth cohorts) | Total | |||
Cases | Controls | Cases | Controls | Cases | Controls | |
n | 182 | 542 | 110 | 330 | 292 | 872 |
Year of birth, mean (SD) | 1919 (7.3) | 1919 (7.3) | 1935 (5.5) | 1935 (5.5) | 1925 (10.0) | 1925 (10.0) |
Year of hiring, mean (SD) | 1950 (4.3) | 1950 (4.3) | 1957 (8.6) | 1957 (8.0) | 1953 (7.0) | 1953 (6.6) |
Age at hire, mean (SD) | 31.1 (8.8) | 31.4 (8.7) | 22.0 (6.5) | 22.0 (5.7) | 27.7 (9.1) | 27.9 (8.9) |
Age at index date*, mean (SD) | 55.2 (5.8) | 55.3 (5.7) | 47.9 (6.6) | 47.9 (6.6) | 52.5 (7.1) | 52.5 (7.0) |
Time since hire, mean (SD) | 24.1 (8.7) | 23.9 (8.7) | 25.9 (9.0) | 26.0 (8.5) | 24.8 (8.9) | 24.7 (8.7) |
Last smoking status, n (%) | ||||||
Non-smoker | 14 (7.7) | 116 (21.4) | 6 (5.5) | 81 (24.5) | 20 (6.8) | 197 (22.6) |
Ex-smoker | 28 (15.4) | 68 (12.5) | 13 (11.8) | 48 (14.5) | 41 (14.0) | 116 (13.3) |
Smoker | 123 (67.6) | 245 (45.2) | 89 (80.9) | 164 (49.7) | 212 (72.6) | 409 (46.9) |
Unknown | 17 (9.3) | 113 (20.8) | 2 (1.8) | 37 (11.2) | 19 (6.5) | 150 (17.2) |
Diabetes mellitus†, n (%) | 15 (8.2) | 7 (1.3) | 12 (10.9) | 8 (2.4) | 27 (9.3) | 15 (1.7) |
Hypertension†, n (%) | 57 (31.3) | 108 (19.9) | 39 (35.5) | 83 (25.2) | 96 (32.9) | 191 (21.9) |
Hypercholesterolaemia†, n (%) | 3 (1.6) | 8 (1.5) | 13 (11.8) | 5 (1.5) | 16 (5.5) | 13 (1.5) |
Obesity‡, n (%) | 17 (9.3) | 59 (10.9) | 21 (19.1) | 44 (13.3) | 38 (13.0) | 103 (11.8) |
Erythocyte sedimentation rate, earliest/baseline measure | ||||||
Elevated §, n (%) | 43 (24.9) | 86 (16.2) | 21 (19.1) | 30 (9.1) | 64 (21.9) | 116 (13.3) |
1 hour, mean (SD) | 8.6 (12.0) | 6.8 (8.6) | 7.3 (10.1) | 5.9 (11.1) | 8.1 (11.3) | 6.5 (9.6) |
2 hours, mean (SD) | 17.8 (18.6) | 14.8 (14.5) | 16.3 (17.0) | 12.6 (15.0) | 17.2 (18.0) | 14.0 (14.7) |
Metabolic syndrome¶, n (%) | 7 (3.8) | 5 (0.9) | 7 (6.4) | 6 (1.8) | 14 (4.8) | 11 (1.3) |
Cumulative RQ** (mg/m3-years), mean (SD) | 12.94 (8.91) | 13.18 (9.77) | 9.12 (8.68) | 8.42 (8.23) | 11.5 (9.00) | 11.38 (9.50) |
*Date of cases’ diagnosis of first acute myocardial infarction, date when the control was the same age as the case at his diagnosis.
†Ascertained by diagnosis, medication or measured ≥3 times (5 years prior to the index date).
‡Body mass index ≥30 measured ≥3 times (5 years prior to the index date).
§Elevated: 1-hour value >10 mm and 2-hour value >20 mm.
¶≥3 criteria fulfilled 5 years prior to the index date (obesity, hypertension, diabetes, hypercholesterolaemia).
**Until 5 years prior to the index date .
RQ, respirable quartz.