Cancer mortality and estimated exposure to styrene, International Agency for Research on Cancer cohort of reinforced plastics workers exposed to styrene, 1945–1991
| Lung | Oesophagus | Pancreas | Prostate | |||||||||
| RR* | 95% CI | AIC | RR | 95% CI | AIC | RR | 95% CI | AIC | RR | 95% CI | AIC | |
| Cumulative styrene exposure (100 ppm-years) | ||||||||||||
| 0-year lag | 1.02 | 0.99 to 1.05 | 3099 | 1.06 | 0.97 to 1.16 | 298.6 | 1.03 | 0.97 to 1.10 | 612.4 | 1.03 | 0.96 to 1.10 | 538.5 |
| 10-year lag | 1.03 | 0.99 to 1.06 | 3099 | 1.08 | 0.98 to 1.19 | 298.2 | 1.03 | 0.96 to 1.11 | 612.6 | 1.00 | 0.92 to 1.10 | 539.2 |
| 20-year lag | 1.00 | 0.91 to 1.09 | 3100 | 1.16 | 1.03 to 1.31 | 296.8 | 1.01 | 0.84 to 1.22 | 613.2 | 0.97 | 0.76 to 1.23 | 539.2 |
| Mean styrene exposure (100 ppm) | ||||||||||||
| 0-year lag | 0.98 | 0.79 to 1.22 | 3100 | 2.44 | 1.11 to 5.36 | 294.8 | 1.89 | 1.17 to 3.06 | 606.4 | 1.26 | 0.76 to 2.11 | 538.3 |
| 10-year lag | 0.97 | 0.80 to 1.18 | 3100 | 2.53 | 1.30 to 4.90 | 293.0 | 1.31 | 0.82 to 2.10 | 611.9 | 1.03 | 0.64 to 1.68 | 539.2 |
| 20-year lag | 0.81 | 0.59 to 1.12 | 3101 | 3.36 | 1.74 to 6.49 | 290.9 | 1.14 | 0.57 to 2.28 | 613.1 | 1.07 | 0.55 to 2.10 | 539.2 |
*RR per 100 ppm-year or 100 ppm. RRs adjusted as follows: NHL, age, calendar decade, sex; lung cancer, age, sex, country; oesophageal cancer, pancreatic cancer: age; prostate cancer: age, country.
AIC, Akaike information criterion; NHL, non-Hodgkin’s lymphoma; RR, rate ratio.