Table 2

Overview of study characteristics and effectiveness

PublicationTarget groupIntervention contentDuration of interventionFidelity>75%Intervention given byContains:OutcomeEffective
Org. changeGraded return to workTherapyWork place contact
High-quality RCTs
Brouwers et al 23
(n=194)
CMD (depressive disorders, anxiety disorders and emotional distress)Early intervention focused on problem solving and copingFive sessions (50 min) over the course of 10 weeksYesSocial workersXTime until RTWNo
Fleten et al 18 (n=169)CMD (depressive disorders and other mental disorders)Minimal intervention: letters containing generic information about sick leave and a questionnaireYesTime until RTWYes
Reme et al 20 (n=1193)CMD (depression and anxiety symptoms)Integrated CBT and Individual Placement and Support (IPS)Up to 15 sessionsYesTherapists and caseworkersXXXXFull RTW at 12 monthsYes
van der Feltz-Cornelis et al 19 (n=60)CMD (depressive disorders, anxiety disorders and somatoform disorders)Training of occupational physicians in diagnosing and treating CMDs. Training of psychiatrists in facilitating RTWOccupational physicians and psychiatristsTime until RTWYes
Volker et al 21 (n=216)CMD (depressive disorders, anxiety disorders and somatoform disorders)Online intervention consisting of psychoeducation and with a focus on addressing RTW6–17 online sessions, that could be completed at any timeNoXTime until RTWNo
Bakker et al 25 (n=433)StressBrief training of primary care physicians in giving advice on achieving RTWUp to t consultationsNoPrimary care physiciansTime until RTWNo
van Oostrom et al 26 (n=145)StressReferral to an RTW-coordinator, who facilitated contact to the work place and aided in problem solving~1 monthYesRTW coordinators (social worker or labour expert)XTime until RTWNo
Hees et al 24 (n=117)DepressionIndividual and group sessions with an occupational therapist. Intervention focused on facilitating contact to the work place and engaging in simulated work situations18 sessionsYesOccupational therapistsXXFull RTW at 18 monthsNo
Vlasveld et al 27 (n=126)DepressionCollaborative care provided by occupation care manager. Focus on problem solving, guided self-help and interventions at the work place6–12 sessionsNoOccupational physician care managersXXTime until RTW and full RTW at 12 monthsNo
Hellström et al 22 (n=326)Depression and anxietyIndividual Placement and Support (IPS) modified to fit workers with depression and anxiety disordersYesMentors (nurses, social workers or occupational therapists)XXXFull RTW at 12 monthsNo
Fair-quality RCTs
de Weerd et al 47 (n=60)CMD (depressive disorders, anxiety disorders, stress-related disorders and somatoform disorders)A meeting focused on problem solving (convergence dialogue meeting) between employee, therapist and employer in addition to treatment as usual (CBT)YesTherapists and caseworkersXTime until RTWNo
Lammerts et al 40 (n=186)CMD (depressive disorders, anxiety disorders and stress-related disorders)Early coordinated intervention focused on problem solving and fast, supported return to work~6 weeksNoRTW-coordinators, insurance physicians and labour expertsXTime until RTWNo
Lytsy et al 42 (n=308)CMD (mental disorders) and painTEAM: Multidisciplinary team develop individualised rehabilitation plan focused on problem solvingYesTEAM: physicians, psychologists, occupational therapists and social workersXNumber of sick-leave days in following 12 monthsNo
 ACT: Acceptance and commitment therapy. Focused on enhancing level of functioning and quality of lifeACT: TherapistsX
Martin et al 38 (n=168)CMD (anxiety disorders, depressive disorders and related mental health problems)Multidisciplinary team is appointed to develop rehabilitation plan with a focus on problem solvingMax 12 weeksNoMultidisciplinary teams (not specified)XFull RTW at 12 monthsNo
Momsen et al 41 (n=443)CMD (CMD not specified and stress-related disorders)Multidisciplinary team is appointed to develop an individualised RTW planYesRTW coordinators and health professionalsXTime until RTWNo
Noordik et al 48 (n=160)CMD (depressive disorders, anxiety disorders, stress-related disorders and adjustment disorders)Gradual exposure to increasing work load (not partial return to work)NoOccupational physiciansXTime until RTWNo
Nystuen et al 43 (n=40)CMD (non-severe psychological problems)Solution focused therapy (individually or in groups)8 weeks (8 sessions of 3–4 hours)PsychologistsXNumber of sick-leave days in following 12 monthsNo
Rebergen et al 49 (n=240)CMD (depressive disorders, anxiety disorders and adjustment disorders)Training of occupational physicians in facilitating RTW through problem solving, gradual return to work and contact to the work place. Based on CBT principles2–20 weeksYesOccupational physiciansTime until RTWNo
van Beurden et al 35 (n=3228)CMD (depressive disorders, anxiety disorders, stress-related disorders and other mental disorders)Training of occupational physicians in following guidelines: see patient, evaluate treatment, prevent recurrences and evaluate process8 sessions over the course of 12 monthsOccupational physiciansTime until RTWNo*
Beck et al 46 (n=20)StressPsychotherapy using music to reduce stress6 session over the course of 9 weeksYesTherapistXSelf-reported work readinessNo
Blonk et al 29 (n=128)StressTraditional CBT11 sessions (45 min) over the course of ~6 weeksPsychologistsXTime until RTWNo
 CBT combined with advice from labour experts on work processes, stress management and RTW5–6 sessions (1 hour) over the course of ~3 weeksPsychologists and labour expertsXYes
De Vente et al 44 (n=82)StressStress-management intervention based on CBT (individual)YesPsychologistsXNumber of sick-leave days in following 4 monthsNo
 Stress-management intervention based on CBT (group)
Netterstrøm et al 51 (n=140)StressStress-inoculation intervention and mindfulness-based training combined with contact to the work placeStress treatment (3 months) and mindfulness-based stress intervention (8 weeks)YesOccupational physicians and psychologistsXXXFull RTW at 3  monthsYes
Netterstrøm et al 33 (n=117)StressStress therapy concept of Kalmia and mindfulness-based training combined with work place dialogue10 weeksYesTherapistsXXFull RTW at 3 monthsYes
Stenlund et al 50 (n=136)StressCognitive behavioural rehabilitation (CBR) in addition to treatment as usual (Qigong; mind-body training)CBR and one weekly Qigong session (1 hour) for a yearYesPhysiotherapist trained in QigongXProportion sick-listed at 12 monthsNo
Van der Klink et al 28 (n=192)StressTraining of occupational physicians in giving CBT-intervention focused on problem solving and contact to the work place4–5 consultations (90 min) within the first 6 weeks of sick leaveYesOccupational physiciansXXTime until RTW and full RTW at 3 monthsYes
Willert et al 31 (n=87)StressStress-inoculation intervention8 sessions over the course of ~3 monthsNoPsychologistsXNumber of sick-leave days in following 4 monthsYes
Folke et al 45 (n=34)DepressionAcceptance and commitment therapy (group)6 sessionsPsychologistsXWork readinessNo
Kröger et al 34 (n=26)DepressionTraining of therapists in giving an intervention aimed at problem solving, facilitating gradual RTW and viewing the work place as a resource. Inclusion of employer and occupational physician if possible24 weekly work-related CBT-sessionsYesTherapists experienced in treating depression and occupational physiciansXXXXSick-leave days
/100
Yes
Schene et al 30 (n=50)DepressionIntervention focused on problem solving, preparation for RTW, contact to the work place and early return to work (if possible)48 weeksYesOccupational physicians and occupational therapistsXXTime until RTWYes
Skouen et al 37 (n=208)Chronic painMultidisciplinary programme consisting of psychoeducation and feedback from multidisciplinary team and follow-up meetings1 hour meeting and three follow-up meetingsMultidisciplinary teams (not specified)XNumber of sick-leave days in following 54 monthsNo
 Multidisciplinary programme consisting of CBT, physical training and interventions at the work place4 weeks (6 hour every day, 5 days a week)XX
Controlled studies
Lagerveld et al 57 (n=168)CMD (adjustment disorders, anxiety disorders, depressive disorders and other mental disorders)Work-related CBT. Focus on the work place as a resource and on facilitating gradual RTW12 sessions over the course of ~5,5 monthsYesPsychologistsXXTime until RTWYes
Schneider et al 59 (n=28 856)CMD (mental disorders)Gradual RTWPhysiciansXTime until RTWYes
Wåhlin et al 58 (n=311)CMD (depressive disorders, anxiety disorders, adjustment disorders and stress-related disorders)Medical, rehabilitating and/or work related intervention-modules (content not specified)????Self-reported work abilityYes
Eklund et al 52 (n=84)StressRehabilitation involving analysis of the participant’s situation, goal setting and RTW16 weeksYesSocial insurance officersXXRTW at 12 monthsYes
Grossi et al 53 (n=24)StressRehabilitation programme consisting of consultations with the course leader, group meetings focused on enhancing coping skills and training in relaxation techniques3 months (½ day of training and ½ day meetings weekly)Social workersXSickness absence at 12 monthsNo
Karlson et al 55 56 (n=148)StressA dialogue-meeting focused on problem solving between worker, team worker and employer and a group seminar on stressMeeting (1,5 hour) and seminar attendance (½ day)Team workers (not specified)XRTW at 80 weeksNo
Netterstrøm et al 32 (n=97)StressAnamnesis, clinical examination, stress management programme, physical training, training in relaxation techniques, a book on stress and facilitation of contact to the work place (in agreement with participant)4 monthsYesLabour expertsXXFull RTW at 4 monthsYes
Suoyrjö et al 54 (n=218)FibromyalgiaCourse for in-patients. Individualised interventions providing psychoeducation about fibromyalgia and aimed at enhancing coping skills15 days over the course of 6 monthsPhysicians, psychologists, physiotherapists, social workers etcXTime until RTWNo
  • *Not for RTW, but for self-reported belief in RTW.

  • CBT, Cognitive Behavioral Therapy; CBR, cognitive behavioural rehabilitation; CMD, common mental disorder; IPS, Individual Placement and Support; RCT, randomised controlled trial; RTW, return to work.