Table 1

Group 1 agents evaluated in the IARC Monographs Volumes 1–120, excluded from primary list of occupational carcinogens

AgentVolume (a)Year (a)Cancers with sufficient evidence in humans (b)
Reason for Exclusion: Group 1 classification based on mechanistic upgrade
Ethylene oxide601994N/A
3,4,5,3’,4’-Pentachlorobiphenyl (PCB-126)100F2012N/A
4,4'-Methylenebis(2-chloroaniline) (MOCA)992010N/A
Benzidine, dyes metabolized to992010N/A
Neutron radiation752000N/A
Reason for Exclusion: Evaluation did not include occupational epidemiology data
AflatoxinsSup 71987Liver
ErioniteSup 71987Mesothelioma
Fission products, including strontium-90100D2012Salivary gland, oesophagus, stomach, colon, lung, bone, basal cell of the skin, female breast, kidney, urinary bladder, brain and CNS, thyroid, leukaemia
Fluoro-edenite fibrous amphibole1112017Mesothelioma
Reason for Exclusion: Group 1 classification is for an occupation, industry, or process
Acheson process, occupational exposure associated with1112017Lung
Aluminium productionSup 71987Lung, bladder
Auramine productionSup 71987Bladder
Coal gasificationSup 71987Lung
Coal-tar distillation922010Skin
Coke productionSup 71987Lung
Haematite mining (underground, with exposure to radon)(c)Sup 71987Lung
Iron and steel founding (occupational exposure during)Sup 71987Lung
Isopropyl alcohol manufacture using strong acidsSup 71987Nasal cavity
Magenta productionSup 71987Bladder
Painter (occupational exposure as a)471989Lung, mesothelioma, bladder
Rubber manufacturing industry (occupational exposures in)Sup 71987Leukaemia, lymphoma, lung, stomach, bladder