All | Men aged 15–50 | Women aged 15–50 | |||||
Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | p* | |
Excretion rate constant (per year)† | |||||||
PFHxS | 0.13 | 0.12 to 0.15 | 0.09 | 0.07 to 0.11 | 0.15 | 0.12 to 0.18 | 0.008 |
PFOS | 0.20 | 0.19 to 0.22 | 0.15 | 0.11 to 0.18 | 0.22 | 0.19 to 0.26 | 0.004 |
PFOA | 0.26 | 0.24 to 0.28 | 0.25 | 0.19 to 0.26 | 0.29 | 0.23 to 0.34 | 0.29 |
Half-life (years)‡ | |||||||
PFHxS | 5.3 | 4.6 to 6.0 | 7.4 | 6.0 to 9.7 | 4.7 | 3.9 to 5.9 | 0.008 |
PFOS | 3.4 | 3.1 to 3.7 | 4.6 | 3.7 to 6.1 | 3.1 | 2.7 to 3.7 | 0.004 |
PFOA | 2.7 | 2.5 to 2.9 | 2.8 | 2.4 to 3.4 | 2.4 | 2.0 to 3.0 | 0.29 |
The subgroup aged 15–50 includes 20 men and 30 women.
*p Values for the difference between genders in the model for excretion rate.
†The estimates in the table are adjusted for age, gender and body mass index in a mixed-effects model.
‡Half-life values are all calculated from excretion rate constant.
PFAS, perfluorinated and polyfluorinated substance; PFHxS, perfluorohexane sulfonate; PFOA, perfluorooctanoate; PFOS, perfluorooctane sulfonate.