Connective and soft tissue cancers, n=20 | Cirrhosis of the liver, n=97 | NMRD, n=430 | COPD, n=248 | |||||||||
n | HR | 95% CI | n | HR | 95% CI | n | HR | 95% CI | n | HR | 95% CI | |
Cumulative exposure* | ||||||||||||
<63 ppm-years | 1 | Ref | – | 11 | Ref | – | 62 | Ref | – | 35 | Ref | – |
63 to <287 ppm-years | 1 | 1.0 | 0.1 to 16.7 | 19 | 1.8 | 0.9 to 3.8 | 85 | 1.4 | 1.0 to 2.0 | 56 | 1.7 | 1.1 to 2.5 |
287 to <865 ppm-years | 3 | 2.9 | 0.3 to 28.0 | 22 | 2.0 | 1.0 to 4.1 | 93 | 1.4 | 1.0 to 1.9 | 59 | 1.6 | 1.0 to 2.4 |
865 to <2271 ppm-years | 5 | 4.6 | 0.5 to 39.5 | 24 | 2.1 | 1.0 to 4.3 | 100 | 1.4 | 1.0 to 1.9 | 52 | 1.3 | 0.8 to 1.9 |
≥2271 ppm-years | 10 | 8.9 | 1.1 to 69.8 | 21 | 1.7 | 0.9 to 3.7 | 90 | 1.1 | 0.8 to 1.5 | 46 | 1.0 | 0.6 to 1.5 |
*Quintiles of cumulative exposure based on distributions among the full cohort, n=9951.
†All models unadjusted.
COPD, chronic obstructive pulmonary disease; NHL, non-Hodgkin’s lymphoma; NMRD, non-malignant respiratory disease; ppm, parts per million; Ref, referent.