Analysis of the synergistic effect of obesity and physical work load on disability benefit among construction workers with a normal body weight or obesity (n=2 32 291) and among construction workers with a normal body weight or overweight (n=314 424).
| Disability benefit diagnosis | |||||
| All, HR (95% CI) | CVD, HR (95% CI) | MSD, HR (95% CI) | Mental disorders, HR (95% CI) | Other, HR (95% CI) | |
| Healthy weight: low/intermediate physical workload | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Healthy weight:high physical workload | 1.59 (1.55 to 1.63) | 1.28 (1.19 to 1.37) | 1.93 (1.86 to 2.00) | 1.11 (1.04 to 1.19) | 1.45 (1.38 to 1.52) |
| Overweight: low/intermediate physical workload | 1.22 (1.19 to 1.26) | 1.44 (1.34 to 1.56) | 1.29 (1.23 to 1.34) | 0.93 (0.85 to 1.03) | 1.18 (1.11 to 1.25) |
| Overweight: high physical workload | 1.91 (1.86 to 1.96) | 1.89 (1.76 to 2.03) | 2.40 (2.31 to 2.50) | 1.00 (0.92 to 1.10) | 1.59 (1.51 to 1.67) |
| Obesity: low/ intermediate physical workload | 1.78 (1.69 to 1.88) | 2.35 (2.09 to 2.65) | 1.81 (1.68 to 1.95) | 1.19 (0.98 to 1.46) | 1.71 (1.55 to 1.88) |
| Obesity: high physical workload | 2.65 (2.53 to 2.77) | 2.89 (2.58 to 3.23) | 3.19 (3.00 to 3.39) | 1.41 (1.18 to 1.68) | 2.23 (2.04 to 2.43) |
| RERI: overweight and physical workload (95% CI) | 0.10 (0.05 to 0.15) | 0.16 (0.03 to 0.30) | 0.18 (0.10 to 0.26) | −0.04 (−0.16 to 0.08) | −0.04 (−0.13 to 0.05) |
| RERI: obesity and physical workload (95% CI) | 0.28 (0.14 to 0.41) | 0.26 (−0.12 to 0.63) | 0.44 (0.23 to 0.66) | 0.10 (−0.24 to 0.43) | 0.08 (−0.16 to 0.32) |
Adjusted for age and smoking.
CVD, cardiovascular disease; MSD, musculoskeletal diseases; RERI, relative excess risk due to interaction.