Occupational exposure to biocides and pesticides and risk of thyroid cancer by gender
| Occupational exposure | Female | Male | P for interaction | |||||||||||
| Cases | Controls | OR* (95% CI) | Cases | Controls | OR* (95% CI) | |||||||||
| Biocides | ||||||||||||||
| Never | 157 | 170 | 1.00 | 44 | 92 | 1.00 | ||||||||
| Uncertain | 112 | 95 | 1.44 (0.99 to 2.11) | 25 | 51 | 1.10 (0.57 to 2.09) | ||||||||
| Ever | 103 | 77 | 1.48 (1.00 to 2.19) | 18 | 11 | 3.11 (1.25 to 7.72) | 0.18 | |||||||
| Probability | ||||||||||||||
| Average | ||||||||||||||
| Low | 24 | 24 | 1.02 (0.53 to 1.95) | 8 | 6 | 2.19 (0.65 to 7.43) | ||||||||
| Medium | 36 | 24 | 1.61 (0.89 to 2.94) | 9 | 4 | 5.31 (1.39 to 20.29) | ||||||||
| High | 43 | 29 | 1.77 (1.02 to 3.09) | 1 | 1 | 1.46 (0.07 to 28.82) | ||||||||
| p for trend† | 0.16 | 0.45 | 0.22 | |||||||||||
| Cumulative | ||||||||||||||
| Low | 25 | 22 | 1.13 (0.58 to 2.17) | 9 | 7 | 2.16 (0.68 to 6.84) | ||||||||
| Medium | 35 | 29 | 1.22 (0.68 to 2.18) | 6 | 1 | 9.82 (0.99 to 97.51) | ||||||||
| High | 43 | 26 | 2.13 (1.20 to 3.79) | 3 | 3 | 3.33 (0.59 to 18.82) | ||||||||
| p for trend† | 0.092 | 0.70 | 0.23 | |||||||||||
| Intensity | ||||||||||||||
| Average | ||||||||||||||
| Low | 31 | 26 | 1.17 (0.63 to 2.15) | 7 | 4 | 3.63 (0.92 to 14.32) | ||||||||
| Medium | 54 | 36 | 1.75 (1.05 to 2.90) | 6 | 3 | 3.37 (0.72 to 15.76) | ||||||||
| High | 18 | 15 | 1.40 (0.64 to 3.06) | 5 | 4 | 2.37 (0.53 to 10.61) | ||||||||
| p for trend† | 0.59 | 0.39 | 0.23 | |||||||||||
| Cumulative | ||||||||||||||
| Low | 31 | 28 | 1.07 (0.59 to 1.94) | 5 | 4 | 1.76 (0.41 to 7.60) | ||||||||
| Medium | 32 | 24 | 1.53 (0.83 to 2.82) | 8 | 3 | 6.26 (1.35 to 28.93) | ||||||||
| High | 40 | 25 | 1.95 (1.08 to 3.52) | 5 | 4 | 2.61 (0.58 to 11.71) | ||||||||
| p for trend†I | 0.27 | 0.69 | 0.25 | |||||||||||
| Pesticides | ||||||||||||||
| Never | 284 | 272 | 1.00 | 63 | 113 | 1.00 | ||||||||
| Uncertain | 86 | 64 | 1.25 (0.84 to 1.86) | 19 | 36 | 1.14 (0.57 to 2.32) | ||||||||
| Ever | 2 | 6 | 0.26 (0.04 to 1.61) | 5 | 5 | 3.33 (0.80 to 13.85) | 0.48 | |||||||
*Adjusted for age (continuous), gender, race, education, body mass index, family history of thyroid cancer, history of benign thyroid disease, smoking status, alcohol consumption and physical activity.
†Calculated by continuous variables among exposed participants.