PRs and 95% CIs of COPD risk spirometry defined as FEV1/FVC<LLN for exposure to current job codified as four-digit SOC code 2000 in the UK Biobank study (n=228 614)
| SOC code | Occupations | Healthy exposed | Cases exposed | PR | 95% CI | |
|---|---|---|---|---|---|---|
| 8217 | Seafarers; barge, lighter and boat operatives | 32 | 10 | 2.64 | 1.59 | 4.38 |
| 8122 | Coal mine operatives | 13 | 5 | 2.30 | 1.00 | 5.31 |
| 9132 | Industrial cleaning process occupations | 34 | 10 | 1.96 | 1.16 | 3.31 |
| 5313 | Roofers, roof tilers and slaters | 102 | 22 | 1.86 | 1.29 | 2.67 |
| 9134 | Packers, bottlers, canners, fillers | 153 | 30 | 1.60 | 1.15 | 2.22 |
| 5112 | Horticultural trades | 84 | 14 | 1.55 | 0.97 | 2.50 |
| 8111 | Food, drink and tobacco process operatives | 296 | 45 | 1.46 | 1.11 | 1.93 |
| 9233 | Cleaners, domestics | 1715 | 302 | 1.43 | 1.28 | 1.59 |
| 5322 | Floorers and wall tilers | 160 | 27 | 1.41 | 1.00 | 2.00 |
| 8114 | Chemical and related process operatives | 218 | 29 | 1.39 | 0.98 | 1.97 |
| 9211 | Postal workers, mail sorters, messengers, couriers | 962 | 137 | 1.35 | 1.15 | 1.59 |
| 9121 | Labourers in building and woodworking trades | 376 | 59 | 1.32 | 1.04 | 1.68 |
| 9244 | School mid-day assistants | 363 | 52 | 1.32 | 1.01 | 1.74 |
| 9223 | Kitchen and catering assistants | 865 | 127 | 1.30 | 1.10 | 1.53 |
PRs and 95% CIs for exposure to each four-digit SOC code and COPD risk (defined as FEV1/FVC<LLN) were calculated by using a Poisson model with robust variance adjusted for sex, study centre (22 categories), age (5 years categories) and lifetime smoking exposure (ever, pack-years and years since quitting). Reference category: current workers not employed in the specific four-digit SOC-coded job tested. Healthy=non-COPD cases.
COPPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; LLN, lower limit of normal; PR, prevalence ratio; SOC, Standard Occupational Classification.