Estimates of the expected change during follow-up for lung function z-scores per unit change in predictor variables, when comparing farmers with controls (n=1058)
| Regression model | ΔzFEV1 (R2=0.13) | ΔzFVC (R2=0.23) | ΔzFEV1/FVC (R2=0.06) | |||
|---|---|---|---|---|---|---|
| E (95% CI) | p Value | E (95% CI) | p Value | E (95% CI) | p Value | |
| Control | 0 | – | 0 | – | 0 | – |
| Farmer status | ||||||
| Ex | 0.05 (−0.07 to 0.16) | 0.414 | −0.05 (−0.16 to 0.06) | 0.393 | 0.14 (−0.01 to 0.29) | 0.074 |
| Current | −0.07 (−0.19 to 0.05) | 0.272 | −0.09 (−0.21 to 0.03) | 0.139 | −0.01 (−0.17 to 0.15) | 0.932 |
| Smoking | ||||||
| Ex-smoker | 0.04 (−0.10 to 0.18) | 0.573 | −0.06 (−0.20 to 0.08) | 0.402 | 0.15 (−0.04 to 0.34) | 0.123 |
| Current low | −0.11 (−0.23 to 0.01) | 0.081 | −0.01 (−0.12 to 0.11) | 0.906 | −0.15 (−0.31 to 0.01) | 0.065 |
| Current high | −0.24 (−0.35 to −0.14) | 0.000 | −0.10 (−0.21 to −0.003) | 0.044 | −0.20 (−0.33 to −0.06) | 0.005 |
| Second-hand smoking | −0.08 (−0.16 to 0.01) | 0.069 | −0.09 (−0.17 to −0.01) | 0.025 | 0.04 (−0.07 to 0.15) | 0.465 |
| Raised on a farm | 0.10 (0.01 to 0.18) | 0.025 | 0.08 (−0.000 to 0.16) | 0.050 | 0.06 (−0.05 to 0.17) | 0.274 |
| Baseline BHR | −0.09 (−0.22 to 0.04) | 0.190 | −0.13 (−0.26 to −0.005) | 0.042 | 0.01 (−0.16 to 0.19) | 0.876 |
| Follow-up BMI | −0.05 (−0.06 to −0.04) | 0.000 | −0.07 (−0.08 to −0.06) | 0.000 | 0.03 (0.02 to 0.05) | 0.000 |
Bold shows significance p<0.05.
BHR, bronchial hyper responsiveness; BMI, body mass index; E, estimate; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.