Any OP use | |||||||
---|---|---|---|---|---|---|---|
Total | No | Yes | |||||
N=29 325 | N=21 736 | N=7589 | |||||
N | Per cent | N | Per cent | N | Per cent | p Value† | |
Age at enrolment | |||||||
≤35 | 5740 | 19.6 | 4743 | 21.8 | 997 | 13.1 | <0.01 |
36–45 | 8829 | 30.1 | 6465 | 29.7 | 2364 | 31.2 | |
46–55 | 7493 | 25.6 | 5172 | 23.8 | 2321 | 30.6 | |
56+ | 7263 | 24.8 | 5356 | 24.6 | 1907 | 25.1 | |
State | |||||||
Iowa | 19 880 | 67.8 | 14 323 | 65.9 | 5557 | 73.2 | <0.01 |
North Carolina | 9445 | 32.2 | 7413 | 34.1 | 2032 | 26.8 | |
Race | |||||||
White | 28 757 | 98.1 | 21 208 | 97.6 | 7549 | 99.5 | <0.01 |
Other | 520 | 1.8 | 489 | 2.3 | 31 | 0.4 | |
Missing | 48 | 0.2 | 39 | 0.2 | 9 | 0.1 | |
Cigarette smoking (pack-years) | |||||||
Never smoker | 20 607 | 70.3 | 15 304 | 70.4 | 5303 | 69.9 | 0.06 |
Q1: ≤1.5 | 1894 | 6.5 | 1361 | 6.3 | 533 | 7.0 | |
Q2: 1.51–6.625 | 1973 | 6.7 | 1456 | 6.7 | 517 | 6.8 | |
Q3: 6.626–18 | 2049 | 7.0 | 1551 | 7.1 | 498 | 6.6 | |
Q4: >18 | 1802 | 6.1 | 1311 | 6.0 | 491 | 6.5 | |
Missing | 1000 | 3.4 | 753 | 3.5 | 247 | 3.3 | |
Educational attainment | |||||||
High school or less | 11 983 | 40.9 | 9117 | 41.9 | 2866 | 37.8 | <0.01 |
Some college | 8010 | 27.3 | 5914 | 27.2 | 2096 | 27.6 | |
College graduate | 6302 | 21.5 | 4623 | 21.3 | 1679 | 22.1 | |
Other/missing | 3030 | 10.3 | 2082 | 9.6 | 948 | 12.5 | |
Alcohol use | |||||||
Never | 13 135 | 44.8 | 10 095 | 46.4 | 3040 | 40.0 | <0.01 |
Less than once/month | 7799 | 26.6 | 5667 | 26.0 | 2132 | 28.1 | |
1–3 times/month | 4579 | 15.6 | 3321 | 15.3 | 1258 | 16.6 | |
1 time/week or more | 3480 | 11.9 | 2401 | 11.0 | 1079 | 14.2 | |
Missing | 332 | 1.1 | 252 | 1.2 | 80 | 1.1 | |
Body mass index | |||||||
≤25 | 12 853 | 43.8 | 9514 | 43.8 | 3339 | 44.0 | <0.01 |
25.1–30 | 8285 | 28.3 | 5936 | 27.3 | 2349 | 31.0 | |
>30 | 4795 | 16.4 | 3491 | 16.1 | 1304 | 17.2 | |
Missing | 3392 | 11.6 | 2795 | 12.9 | 597 | 7.9 | |
Family history of cancer | |||||||
No | 14 356 | 49.0 | 10 943 | 50.4 | 3413 | 45.0 | <0.01 |
Yes | 14 426 | 49.2 | 10 343 | 47.6 | 4083 | 53.8 | |
Missing | 543 | 1.9 | 450 | 2.1 | 93 | 1.2 | |
Menopause at enrolment | |||||||
No | 14 841 | 50.6 | 11 130 | 51.2 | 3711 | 48.9 | <0.01 |
Yes, before age 50 | 7086 | 24.2 | 5022 | 23.1 | 2064 | 27.2 | |
Yes, after age 50 | 4101 | 14.0 | 2870 | 13.2 | 1231 | 16.2 | |
Missing | 3297 | 11.2 | 2714 | 12.5 | 583 | 7.7 | |
Number of live births | |||||||
0 | 1554 | 5.3 | 1149 | 5.3 | 405 | 5.3 | <0.01 |
1 | 2194 | 7.5 | 1711 | 7.9 | 483 | 6.4 | |
2 | 8625 | 29.4 | 6347 | 29.2 | 2278 | 30.0 | |
3 | 6961 | 23.7 | 4944 | 22.8 | 2017 | 26.6 | |
4+ | 5585 | 19.1 | 3949 | 18.2 | 1636 | 21.6 | |
Missing | 4406 | 15.0 | 3636 | 16.7 | 770 | 10.2 | |
Oral contraceptive use | |||||||
Never | 6838 | 23.3 | 5049 | 23.2 | 1789 | 23.6 | <0.01 |
Ever | 19 124 | 65.2 | 13 938 | 64.1 | 5186 | 68.3 | |
Missing | 3363 | 11.5 | 2749 | 12.7 | 614 | 8.1 | |
Apply pesticides in home | |||||||
No | 21 164 | 72.2 | 16 833 | 77.4 | 4331 | 57.1 | <0.01 |
Yes | 8161 | 27.8 | 4903 | 22.6 | 3258 | 42.9 | |
Apply pesticides on lawn/garden | |||||||
No | 26 158 | 89.2 | 20 417 | 93.9 | 5741 | 75.7 | <0.01 |
Yes | 3167 | 10.8 | 1319 | 6.1 | 1848 | 24.4 |
*Excluded n=678 women missing information on any OP use. The overall study population included 30 003 women, as there were some women who had valid exposure information for a single OP but were missing data for overall OP use.
†χ2 Test for homogeneity.
AHS, Agricultural Health Study; OP, organophosphates.