Predicted effect of work cessation on FEV1 by gender, occupational exposure, and smoking status based on a generalised additive mixed model
| Cessation years | Change in FEV1, mL (95% CI) | |||||||
|---|---|---|---|---|---|---|---|---|
| Silk non-smokers | Silk smokers | Cotton non-smokers | Cotton smokers | |||||
| Men | ||||||||
| 5 | 28.7 | (−14.5 to 71.9) | −2.3 | (−35.5 to 30.9) | 15.6 | (−28.3 to 59.4) | −76.8 | (−113.4 to −40.2) |
| 10 | 73.2 | (11.8 to 134.6) | 46.2 | (4.2 to 88.3) | 49.0 | (−11.8 to 109.8) | −3.7 | (−48.4 to 41.0) |
| 15 | 152.7 | (74.8 to 230.6) | 146.8 | (95.7 to 197.8) | 134.4 | (59.1 to 209.7) | 61.9 | (7.1 to 116.7) |
| 20 | 265.2 | (154.1 to 376.2) | 227.3 | (155.1 to 299.6) | 223.2 | (124.3 to 322.2) | 103.0 | (26.1 to 179.8) |
| 25 | 391.8 | (214.2 to 569.4) | 280.8 | (161.3 to 400.4) | 308.0 | (159.5 to 456.6) | 187.8 | (76.8 to 298.7) |
| Women | ||||||||
| 5 | 66.1 | (43.8 to 88.4) | 67.8 | (−21.8 to 157.3) | 47.4 | (24.4 to 70.4) | 42.1 | (−1.0 to 85.1) |
| 10 | 135.2 | (103.8 to 166.7) | 135.5 | (−43.6 to 314.6) | 112.0 | (79.6 to 144.3) | 84.1 | (−1.9 to 170.2) |
| 15 | 213.9 | (175.0 to 252.8) | 203.3 | (−65.4 to 472.0) | 185.7 | (145.5 to 226.0) | 126.2 | (−2.9 to 255.3) |
| 20 | 313.9 | (264.1 to 363.8) | 271.0 | (−87.2 to 629.3) | 273.7 | (221.3 to 326.0) | 168.3 | (−3.8 to 340.4) |
| 25 | 426.1 | (358.7 to 493.4) | 338.8 | (−109 to 786.6) | 373.2 | (302.3 to 444.2) | 210.4 | (−4.8 to 425.5) |
Predictions are for eight hypothetical workers of different gender, smoking and occupational (cotton vs silk) exposures. Predictions assume that these workers have the same age, height, pack-year history (zero if non-smokers, the average number of pack-years if smokers) at each value of work cessation-years. Values represent the adjusted change in FEV1 (95% CI), in mL, for that value of work cessation-year, as compared to active work.
FEV1, forced expiratory volume in 1 s.