Table 3

Mortality of cohort from specific cancers, 1946–2012

Cancer*	ICD codes		All workers				Workers with more than background exposure to styrene
Cancer*	ICD 9	ICD 10	Deaths observed	Deaths expected	SMR	95% CI	Deaths observed	Deaths expected	SMR	95% CI
Pharynx†	146–149.1	C09–C14.2	9	6.7	1.34	0.61 to 2.54	7	4.6	1.51	0.61 to 3.11
Oesophagus	150	C15	47	44.2	1.06	0.78 to 1.41	35	30.3	1.16	0.80 to 1.61
Stomach	151	C16	43	57.0	0.75	0.55 to 1.02	31	36.1	0.86	0.58 to 1.22
Large intestine	153	C18	49	63.8	0.77	0.57 to 1.02	36	40.6	0.89	0.62 to 1.23
Rectum	154	C19–C21	33	39.4	0.84	0.58 to 1.18	21	25.7	0.82	0.51 to 1.25
Liver‡	155.0–155.1	C22	16	13.6	1.18	0.67 to 1.91	10	9.4	1.07	0.51 to 1.96
Pancreas	157	C25	48	42.5	1.13	0.83 to 1.50	27	27.6	0.98	0.64 to 1.42
Larynx	161	C32	13	7.6	1.70	0.91 to 2.91	6	5.2	1.15	0.42 to 2.50
Lung	162	C33–C34	329	273.6	1.20	1.08 to 1.34	229	180.2	1.27	1.11 to 1.45
Melanoma†	172	C43	9	10.0	0.90	0.41 to 1.71	4	6.8	0.59	0.16 to 1.51
Breast	174, 175	C50	24	31.2	0.77	0.49 to 1.15	11	11.6	0.95	0.47 to 1.70
Prostate	185	C61	63	73.0	0.86	0.66 to 1.10	44	50.7	0.87	0.63 to 1.17
Bladder†	188	C65–C68	38	32.8	1.16	0.82 to 1.59	28	21.6	1.29	0.86 to 1.87
Kidney†	189	C64	28	21.1	1.33	0.88 to 1.92	18	14.4	1.25	0.74 to 1.98
Brain and nervous system	191, 192	C71–C72	32	24.5	1.31	0.89 to 1.84	26	16.7	1.55	1.02 to 2.28
Hodgkin's disease	201	C81	2	4.1	0.49	0.06 to 1.77	2	2.6	0.75	0.09 to 2.73
Non-Hodgkin's lymphoma†	200.202.0, 202.1, 202.8	C82–C85	24	25.2	0.95	0.61 to 1.42	14	16.9	0.83	0.45 to 1.39
Multiple myeloma†	203.0	C90	13	13.9	0.94	0.50 to 1.60	9	9.1	0.99	0.45 to 1.88
Leukaemia	204–208	C91–C95	23	25.3	0.91	0.58 to 1.36	13	16.7	0.78	0.42 to 1.33
Lymphohaematopoietic cancer	200–208	C81–C96	62	69.8	0.89	0.68 to 1.14	38	46.1	0.82	0.58 to 1.14

*Data are limited to cancers with at least four deaths observed or expected in the analysis for all workers. Results for other cancers can be found in online supplementary table S1.
†Owing to changes in disease classification, the earliest follow-up for these cancers was from 1950.
‡Owing to changes in disease classification, the earliest follow-up for this cancer was from 1958.
ICD, International Classification of Diseases.