Table 1

Best evidence synthesis algorithm/algorithm for messages

Level of evidenceMinimum quality* and quantityConsistencyStrength of message
Strong3 High (H)3H agree; if 3+studies, 3/4 of the M and H agreeRecommendations
Moderate2H or 2H and 1Medium (M)2H agree or 2M and 1H agree;
if 3+, >2/3 of the M and H agree
Practice considerations
Limited1H or 2M or 1M and 1H2 (M and/or H) agree;
if 2+, >1/2 of the M and H agree
Not enough evidence to make recommendations or practice considerations
Mixed2Findings are contradictory
InsufficientMedium-quality studies that do not meet the above criteria
  • *High is >85% in quality assessment; medium is 50–85% in quality assessment.