Table 1

MM cases (N, %) collected by the National Mesothelioma Register (ReNaM) due to familial, environmental and leisure activity exposure by gender, age, anatomical site, period of diagnosis, level of diagnostic certainty, morphology and modalities of interview (Italy, 1993–2008)

	Men		Women
	N	Per cent	N	Per cent
Exposure modalities
Familial	77	20.6	453	52.8
Environmental	217	58.0	297	34.6
Leisure activities	80	21.4	108	12.6
Pleural	348	93.0	801	93.4
Anatomical sites
Peritoneum	23	6.1	56	6.5
Pericardium	0	0.0	1	0.1
Tunica vaginalis of the testis	3	0.8	–	–
Age classes
0–44	24	6.4	36	4.2
45–64	147	39.3	276	32.2
65–74	93	24.9	274	31.9
+75	110	29.4	272	31.7
1993–1996	42	11.2	62	7.2
1997–2000	86	23.0	172	20.0
Period of diagnosis
2001–2004	125	33.4	327	38.1
2005–2008	121	32.4	297	34.6
Diagnostic certainty
MM certain	318	85.0	700	81.6
MM probable or possible	56	15.0	158	18.4
Morphology
Epithelioid	226	60.4	523	61.0
Fibrous	40	10.7	50	5.8
Biphasic	46	12.3	93	10.8
MM NOS	36	9.6	107	12.5
Not available	26	7.0	85	9.9
Exposure detection
Direct interview	200	53.5	392	45.7
Indirect interview	173	46.3	464	54.1
No interview, other information source	1	0.3	2	0.2
Overall	374	100.0	858	100.0

MM, malignant mesothelioma; NOS, not otherwise specified.