Results of adjusted models of relationship between symptoms and lung function abnormalities and exposure variables*
| Health outcome | Exposure variables | OR (95% CI) |
|---|---|---|
| Symptom | ||
| Sinusitis | Use flavourings ingredients | 1.5 (1.0 to 2.4) |
| Use cleaning products | 1.3 (0.8 to 2.1) | |
| WR sinusitis | Time in production areas | 1.7 (0.8 to 3.5) |
| Use flavourings ingredients | 1.9 (0.9 to 4.2) | |
| Use cleaning products | 3.0 (1.3 to 8.0) | |
| Nasal symptoms | Use flavourings ingredients | 1.4 (0.9 to 2.2) |
| Use cleaning products | 1.5 (0.9 to 2.4) | |
| WR nasal symptoms | Time in production areas | 1.2 (0.6 to 2.3) |
| Use flavourings ingredients | 2.2 (1.1 to 4.5) | |
| Use cleaning products | 2.1 (1.0 to 4.6) | |
| Asthma-like symptoms | Time in production areas | 1.5 (0.9 to 2.4) |
| Shortness of breath | Tenure | 2.0 (1.1 to 3.6) |
| WR wheeze | Time in production areas | 1.8 (0.7 to 5.0) |
| Use flavourings ingredients | 2.1 (0.7 to 6.7) | |
| Use cleaning products | 2.0 (0.6 to 7.7) | |
| WR breathing trouble | Time in production areas | 2.7 (1.1 to 7.1) |
| Use flavourings ingredients | 2.8 (1.1 to 7.7) | |
| Usual phlegm | Time in production areas | 2.2 (1.2 to 4.0) |
| Use flavourings ingredients | 1.4 (0.7 to 2.8) | |
| Use cleaning products | 1.5 (0.7 to 3.0) | |
| Usual cough | Time in production areas | 1.9 (1.0 to 3.7) |
| WR usual cough | Time in production areas | 1.8 (0.5 to 7.6) |
| Use flavourings ingredients | 4.7 (1.1 to 33) | |
| Lung function abnormality | ||
| Any spirometric abnormality | Time in production areas | 2.3 (1.1 to 5.3) |
| Low diffusing capacity | Time in production areas | 2.8 (0.9 to 9.4) |
Statistically significant associations are shown in bold.
*Each model includes the exposure variables associated with the health outcome in univariable analyses. Wheeze and breathing trouble were not included in this table as they were not associated with the exposure variables in univariable analyses. Models of symptoms are adjusted for age and smoking status. Models of lung function abnormalities are adjusted for smoking status.
WR, work related.