Comparison of relative risk estimates of current and earlier studies on cancer incidence among firefighters
| Cancer site | Current study SIR (95% CI) | Daniels et al12 SIR (95% CI) | LeMasters et al5 mRR (95% CI) | IARC1 SIR (95% CI) |
|---|---|---|---|---|
| All sites | 1.06 (1.02 to 1.11) | 1.09 (1.06 to 1.12) | 1.05 (1.00 to 1.09) | |
| Buccal cavity and pharynx | 0.92 (0.62 to 1.31)* | 1.32 (1.08 to 1.58)* | 1.23 (0.96 to 1.55) | |
| Stomach | 1.10 (0.91 to 1.30) | 1.15 (0.93 to 1.40) | 1.22 (1.04 to 1.44) | |
| Colon | 1.14 (0.99 to 1.31) | 1.21 (1.09 to 1.34) | 1.21 (1.03 to 1.41) | |
| Rectum | 0.99 (0.82 to 1.19) | 1.11 (0.94 to 1.30) | 1.29 (1.10 to 1.51) | |
| Skin melanoma | 1.25 (1.03 to 1.51) | 0.87 (0.73 to 1.03) | 1.32 (1.10 to 1.57) | |
| Non-melanoma skin | 1.33 (1.10 to 1.59) | 1.39 (1.10 to 1.73) | ||
| Mesothelioma | 1.55 (0.90 to 2.48) | 2.29 (1.60 to 3.19) | ||
| Prostate | 1.13 (1.05 to 1.22) | 1.03 (0.98 to 1.09) | 1.28 (1.15 to 1.43) | 1.30 (1.12 to 1.51) |
| Testicular | 0.51 (0.23 to 0.98) | 0.74 (0.41 to 1.22) | 2.02 (1.30 to 3.13) | 1.47 (1.20 to 1.80) |
| Brain | 0.86 (0.66 to 1.10) | 1.02 (0.76 to 1.34) | 1.32 (1.12 to 1.54) | |
| Non-Hodgkin lymphoma | 1.04 (0.83 to 1.29) | 0.99 (0.84 to 1.15) | 1.51 (1.31 to 1.73) | 1.21 (1.08 to 1.36) |
| Multiple myeloma | 1.13 (0.81 to 1.53) | 0.72 (0.50 to 0.99) | 1.53 (1.21 to 1.94) | |
| Leukaemia | 0.91 (0.71 to 1.22) | 0.94 (0.77 to 1.15) | 1.14 (0.98 to 1.31) |
*Combined SIR for buccal cavity and pharynx.
IARC, International Agency for Research on Cancer; mRR: meta risk ratio (summary risk estimate across all types of incidence and mortality studies5).