Risk of circulatory system disease mortality by exposure to different types* of uranium in the subcohort of 260 smoking workers
Annual exposure status (exposed vs unexposed) | Natural uranium | Reprocessed uranium | ||||
Type F | Type M | Type S | Type F | Type M | Type S | |
HR (95% CI)† | 1.16 (0.45 to 2.99) | 1.85 (0.94 to 3.66) | 1.91 (0.92 to 3.98) | 2.83 (1.19 to 6.77) | 3.15 (1.15 to 8.68) | 4.78 (1.38 to 16.5) |
No. of death cases | 33 | 27 | 16 | 11 | 7 | 6 |
↵* Uranium compounds were classified in terms of absorption types (F-fast, M-moderate or S-slow solubility) according to the Human Respiratory Tract Model15 and to the specific workstations analytical studies.16 17
↵† HRs and 95% CIs estimated using Cox regression models, stratified by sex and birth cohort, adjusted for four-class socioeconomic status and co-exposures to heat, shift work, trichloroethylene and solvents, coded as binary time-dependant variables. Analyses based on 42 observed deaths.