Night shift work characteristic | Cases* (N=141) | Controls* (N=551) | OR† (95% CI) | OR‡ (95% CI) | ||
n | % | n | % | |||
Never | 89 | 63 | 361 | 66 | 1 (Reference) | 1 (Reference) |
Ever | 43 | 31 | 144 | 26 | 1.3 (0.8 to 2.0) | 1.4 (0.9 to 2.1) |
Duration (years§) | ||||||
Never | 88 | 63 | 361 | 66 | 1 (Reference) | 1 (Reference) |
1–5.9 | 13 | 9 | 67 | 12 | 0.9 (0.5 to 1.7) | 0.9 (0.4 to 1.7) |
6–14.9 | 18 | 13 | 48 | 9 | 1.6 (0.9 to 3.0) | 1.7 (0.9 to 3.2) |
≥15 | 12 | 9 | 29 | 5 | 1.8 (0.9 to 3.7) | 2.1 (1.0 to 4.5) |
p For trend | 0.06 | 0.03 | ||||
Cumulative¶ | ||||||
Never | 82 | 58 | 351 | 64 | 1 (Reference) | 1 (Reference) |
<416 | 9 | 6 | 48 | 9 | 0.8 (0.4 to 1.8) | 0.8 (0.4 to 1.9) |
416–1560 | 14 | 10 | 48 | 9 | 1.4 (0.7 to 2.7) | 1.4 (0.7 to 2.9) |
>1560 | 17 | 12 | 43 | 8 | 1.9 (1.0 to 3.5) | 2.3 (1.2 to 4.6) |
p For trend | 0.05 | 0.02 | ||||
Duration and frequency (per week) | ||||||
Never | 82 | 58 | 351 | 64 | 1 (Reference) | 1 (Reference) |
1–2 times; all durations | 15 | 11 | 65 | 12 | 1.0 (0.5 to 1.9) | 1.0 (0.5 to 1.9) |
≥3 times; 1–5.9 years | 9 | 6 | 48 | 9 | 0.9 (0.4 to 2.0) | 1.1 (0.5 to 2.3) |
≥3 times; 6–14.9 years | 11 | 8 | 30 | 5 | 1.8 (0.8 to 3.8) | 2.1 (1.0 to 4.8) |
≥3 times; ≥15 years | 9 | 6 | 16 | 3 | 2.4 (1.0 to 5.6) | 2.5 (1.0 to 6.6) |
p For trend | 0.06 | 0.02 |
↵* Numbers may not add up owing to missing values.
↵† Adjusted for age.
↵‡ Adjusted for age, hormone replacement therapy (0, 1–5, ≥6 years), number of childbirths (0, 1–2, ≥3), age at menarche (<11, 11–14, ≥14 years), years of education (7, 8–9, 10, ≥11), occasional sunbathing frequency (never/rare vs always/more than weekly) and tobacco smoking status (never, current, former).
↵§ Regardless of number per week.
↵¶ Based on tertiles for exposed controls.