Linear regression coefficients of homocysteine and blood pressure in the log-transformed serum PFOA concentration
| Homocysteine (n=2263) | Systolic blood pressure (n=2208) | Diastolic blood pressure (n=2208) | |||||||
| β | SE | p Value | β | SE | p Value | β | SE | p Value | |
| Model 1* | 0.050 | 0.011 | 0.0001 | 2.202 | 0.493 | 0.0001 | 0.784 | 0.433 | 0.081 |
| Model 2† | 0.041 | 0.011 | 0.001 | 2.198 | 0.504 | 0.0001 | 0.747 | 0.447 | 0.105 |
| Model 3‡ | 0.031 | 0.014 | 0.039 | 2.483 | 0.629 | 0.0004 | 0.746 | 0.448 | 0.106 |
↵* Model 1 was adjusted for age, sex, race/ethnicity, education, income, smoking habits and alcohol use.
↵† Model 2 was further adjusted for obesity status, total saturated fatty acid intake, physical activity, serum folate and vitamin B12 levels (only in regressions with homocysteine levels).
↵‡ Model 3 was further adjusted for serum PFOS concentrations, total cholesterol and poor kidney function (assessed by estimated glomerular filtration rate).