Table 4

Glioma risk by glutathione S-transferase genotypes within occupational nonfarm chlorinated solvent exposure groups

Genotype	Solvent exposure						No solvent exposure
	Cases		Controls		OR†	95% CI	Cases		Controls		OR†	95% CI
	No.	%	No.	%	OR†	95% CI	No.	%	No.	%	OR†	95% CI
*GSTM3*	157/316		241/443				159/316		202/443
GSTM3 AA	111	71	170	71	0.91	0.57 to 1.45	119	75	142	70	1.23	0.74 to 2.05
GSTM3 AB or BB	46	29	71	29			40	25	60	30
*GSTP1*	160/322		245/456				162/322		211/456
GSTP1- I105V only‡	69	43	98	40	1.21	0.79 to 1.85	68	42	74	35	1.48	0.93 to 2.34
GSTP1-other genotypes§	91	57	147	60			94	58	137	65
*GSTT1*	159/319		240/450				160/319		210/450
GSTT1-	29	18	33	14	1.40	0.78 to 2.50	26	16	28	13	1.10	0.59 to 2.07
GSTT1+	130	82	207	86	0.72	0.40 to 1.29	134	84	182	87	0.91	0.48 to 1.71

†Adjusted for frequency matching variables (age group, sex) and age and education, within solvent exposure groups.
‡One or two copies of the I105V Ile->Val SNP (rs1695) but no copy of the A114V Ala->Val SNP (rs1138272).
§Neither I105V nor A114V variant or with only A114V Ala->Val SNP.