Exposure metric | Control | BeS | CBD | BeS/CBD |
All participants, n | 127 | 35 | 19 | 54 |
Year of first beryllium exposure | 1970 (1970) | 1973 (1970) | 1973 (1969) | 1973 (1970) |
Years with direct beryllium exposure* | 3.2 (1.3) | 2.1 (0.48) | 3.7 (2.3)§ | 2.6 (1.4) |
Assigned cumulative exposure, μg/m3-years | 3.91 (0.98) | 3.44 (0.26)¶ | 8.79 (2.64)¶ § | 5.33 (0.89) |
Assigned lifetime-weighted average exposure, μg/m3 | 0.13 (0.03) | 0.12 (0.02) | 0.32 (0.11)‡ § | 0.19 (0.04) |
Highest task exposure,† μg/m3 | 1.81 (1.00) | 1.16 (0.26)‡ | 3.75 (1.19)‡ § | 2.07 (0.63) |
Participants never working at K-25, n | 80 | 14 | 10 | 24 |
Year of first beryllium exposure | 1971 (1969) | 1970 (1970) | 1970 (1970) | 1970 (1970) |
Years with direct beryllium exposure* | 3.5 (1.2) | 3.8 (2.4) | 5.7 (4.2)‡ | 4.6 (3.4)¶ |
Assigned cumulative exposure, μg/m3-years | 5.24 (1.02) | 3.88 (2.43) | 15.31 (3.86)‡ | 8.64 (3.08)¶ |
Assigned lifetime-weighted average exposure, μg/m3 | 0.17 (0.03) | 0.15 (0.10) | 0.54 (0.13)‡ | 0.31 (0.12)‡ |
Highest task exposure,† μg/m3 | 2.05 (1.00) | 1.08 (0.38) | 3.27 (1.78) | 1.99 (1.00) |
Values are mean (median).
↵* Years×% time.
↵† Maximum assigned beryllium exposure for any work task regardless of length of exposure.
↵‡ p<0.05 versus controls (Wilcoxon rank sum).
↵§ p<0.05 versus BeS (Wilcoxon rank sum).
↵¶ 0.05<p<0.10 versus controls (Wilcoxon rank sum).
BeS, beryllium sensitisation; CBD, chronic beryllium disease.