Table 1

Characteristics of nickel-cadmium battery workers and biological parameters

France (plant 1)France (plant 2)SwedenUSATotal
N25122111116599
Women, n (%)58 (23.1)49 (22.2)35 (31.5)6 (37.5)148 (24.7)
Age, mean (SD), years47.8 (6.6)45.5 (11.3)40.1 (13.0)44.9 (7.2)45.4 (10.3)
Years of exposure, mean (SD)22.4 (8.1)18.3 (13.2)13.7 (10.2)13.4 (9.7)18.8 (11.3)
Never smoker, n (%)154 (61.4)107 (48.4)59 (53.2)12 (75.0)332 (55.4)
Ex-smokers
 n (%)27 (10.8)31 (14.0)24 (21.6)4 (25.0)86 (14.3)
 Pack-years, mean (SD)8.3 (7.7)15.5 (13.7)11.0 (8.4)14.9 (8.3)11.9 (10.7)
Current smokers
 n (%)70 (27.9)83 (37.6)28 (25.2)0 (0)181 (30.2)
 Pack-years, mean (SD)15.1 (10.2)16.2 (8.2)9.3 (9.8)0 (0)14.7 (9.5)
Urinary creatinine, median (IQR), g/l1.37 (0.93–1.80)1.13 (0.69–1.70)1.47 (1.08–1.90)1.53 (1.07–2.15)1.33 (0.86–1.80)
Urinary Cd, median (IQR)
 μg/l4.72 (2.23–7.84)1.27 (0.54–2.75)1.08 (0.49–2.74)1.48 (0.82–2.73)2.07 (0.86–5.42)
 μg/g creatinine3.40 (1.74–6.40)1.24 (0.51–2.81)0.81 (0.31–1.92)0.98 (0.73–1.31)1.82 (0.75–4.11)
Urinary RBP, median (IQR)
 μg/l168 (108–295)136 (82.0–219)145 (85.6–215)117 (64.5–206)152 (88.5–252)
 μg/g creatinine129 (91.5–194)119 (80.0–180)100 (69.0–140)83.8 (57.0–102)117 (80.4–176)
Urinary, β2-m*, median (IQR)
 μg/l80.0 (36.0–153)72.7 (48.2–119)81.5 (52.0–131)88.0 (26.0–135)79.0 (43.0–132)
 μg/g creatinine69.0 (33.9–132)75.5 (31.7–137)59.2 (39.5–89.8)62.5 (9.90–90.1)66.1 (33.5–122)
  • * n=228, 152, 98, 14 for total of 492.

  • β2-m, concentration of β2-microglobulin; Cd, concentration of cadmium; IQR, interquartile range; RBP, concentration of retinol-binding protein.