Symptoms of allergic disease ages 0–16 years | Occupational exposure group (based on a job exposure matrix) | ||
Reference (n=2692) | Low risk (n=1368) | High risk (n=960) | |
RRR (95% CI) | RRR (95% CI) | RRR (95% CI) | |
(1) Adjusted for sex, father's social class at birth*, region | |||
Eczema (p=0.931) | |||
No | 1 | 1 | 1 |
Yes† | 1 | 1.00 (0.80 to 1.25) | 1.04 (0.82 to 1.32) |
Hay fever (p=0.034) | |||
No | 1 | 1 | 1 |
Yes‡ | 1 | 0.89 (0.73 to 1.07) | 0.76 (0.62 to 0.94) |
Asthma or wheezy bronchitis (p=641) | |||
No | 1 | 1 | 1 |
Symptoms: only in childhood§ | 1 | 1.06 (0.87 to 1.28) | 1.05 (0.85 to 1.28) |
Symptoms: in adolescence¶ | 1 | 1.12 (0.84 to 1.49) | 1.07 (0.78 to 1.47) |
(2) Adjusted for sex, father's social class at birth*, region, school leaving age*, further education on leaving school* | |||
Eczema (p=0.900) | |||
No | 1 | 1 | 1 |
Yes† | 1 | 1.01 (0.80 to 1.27) | 1.06 (0.83 to 1.34) |
Hay fever (p=0.110) | |||
No | 1 | 1 | 1 |
Yes‡ | 1 | 0.94 (0.77 to 1.13) | 0.80 (0.65 to 0.99) |
Asthma or wheezy bronchitis (p=0.559) | |||
No | 1 | 1 | 1 |
Symptoms: only in childhood§ | 1 | 1.07 (0.88 to 1.29) | 1.05 (0.86 to 1.29) |
Symptoms: in adolescence¶ | 1 | 1.14 (0.85 to 1.52) | 1.10 (0.80 to 1.51) |
(3) Adjusted for sex, father's social class at birth*, region, school leaving age*, further education on leaving school* and for each other | |||
Eczema (p=0.814) | |||
No | 1 | 1 | 1 |
Yes† | 1 | 1.00 (0.80 to 1.27) | 1.08 (0.85 to 1.38) |
Hay fever (p=0.063) | |||
No | 1 | 1 | 1 |
Yes‡ | 1 | 0.91 (0.75 to 1.11) | 0.77 (0.62 to 0.96) |
Asthma or wheezy bronchitis (p=0.395) | |||
No | 1 | 1 | 1 |
Symptoms: only in childhood§ | 1 | 1.07 (0.88 to 1.30) | 1.06 (0.87 to 1.31) |
Symptoms: in adolescence¶ | 1 | 1.17 (0.87 to 1.59) | 1.18 (0.85 to 1.64) |
↵* For these variables, missing/unknown categories have been retained in the model to preserve sample size.
↵† Eczema reported at ages 7 (including eczema seen at 7), 11 and/or 16.
↵‡ Hay fever or allergic rhinitis reported at ages 7, 11 and/or 16.
↵§ Asthma and/or wheezy bronchitis ever, reported at ages 7 and/or 11, but no report at the 16-year follow-up of any attacks since 11th birthday.
↵¶ Asthma and/or wheezy bronchitis: most recent attack at ages 11–16 according to parental report at the 16-year follow-up.