OR* of selected histological types of lung cancer for three paint-related exposures, in pooled analyses of two case–control studies in Montreal
| Exposure/histological types of lung cancer | Pooled studies: population controls only† | Pooled studies: population and cancer controls‡ | ||
| Ca/Co | OR (95% CI) | Ca/Co | OR (95% CI) | |
| Total N | 1622/1432 | 1622/1965 | ||
| Metal coatings – any exposure | ||||
| Small cell | 27/118 | 1.1 (0.6 to 2.2) | 27/151 | 1.2 (0.8 to 2.4) |
| Squamous cell | 54/118 | 1.2 (0.5 to 2.4) | 54/151 | 1.4 (0.5 to 2.4) |
| Adenocarcinoma | 28/118 | 0.6 (0.4 to 1.3) | 28/151 | 0.7 (0.3 to 1.5) |
| Wood varnishes and stains – any exposure | ||||
| Small cell | 19/67 | 1.0 (0.5 to 1.9) | 19/93 | 1.2 (0.6 to 2.3) |
| Squamous cell | 45/67 | 1.8 (0.8 to 3.6) | 45/93 | 1.7 (0.9 to 2.8) |
| Adenocarcinoma | 26/67 | 1.4 (0.7 to 2.4) | 26/93 | 1.3 (0.8 to 2.3) |
| Wood and gypsum paints – any exposure | ||||
| Small cell | 35/139 | 0.7 (0.4 to 1.2) | 35/201 | 1.0 (0.4 to 1.4) |
| Squamous cell | 83/139 | 1.6 (0.9 to 2.9) | 83/201 | 1.5 (0.9 to 2.2) |
| Adenocarcinoma | 54/139 | 1.0 (0.6 to 1.5) | 54/201 | 1.1 (0.6 to 1.7) |
↵* OR adjusted for age, family income, ethnicity, respondent status, years of schooling, tobacco smoking and exposure to at least one of the other occupational hazards (asbestos, silica, cadmium compounds). Non-exposure was defined as not exposed to any of the paint-related substances.
↵† For study I we included only the 533 population controls. The statistical model included, in addition to those listed above, a variable for study (I or II).
↵‡ For study I we included all 533 population controls and 533 randomly drawn cancer controls. The statistical model included, in addition to those listed above, a variable for study (I or II).
Ca/Co, cases/controls.