Table 3

Best piecewise log-linear coefficients for 10-year-lagged mean, maximum and cumulative ‘daily weighted average’ (DWA) exposure final models

Log-linear model pieceMean DWA exposure* Mean DWA exposure, excluding professionals and asbestos-exposed* Maximum DWA exposure* Maximum DWA exposure, excluding professionals and asbestos-exposed* Cumulative DWA exposure Cumulative DWA exposure, excluding professionals and asbestos-exposed §
Range 10 to <0.8 μg/m30 to <1 μg/m30 to <200 μg/m3-days
β1, SE2.149, 0.65101.461, 0.85451.377, 0.48621.023, 0.62536.43e–3, 1.79e–37.51e–3, 2.17e–3
Range 20.8 to <1.6 μg/m31 to <9 μg/m3200 to <1000 μg/m3-days
β2, SE−2.750, 0.8896−2.190, 1.246−1.459, 0.5109−1.084, 0.6677−7.05e–3, 1.94e–3−8.03e–3, 2.34e–3
Range 31.6 to <9 μg/m39 to <10 μg/m31000 to <10 000 μg/m3-days
β3, SE0.7282, 0.37980.9845, 0.58681.315, 0.49821.718, 0.75846.63e–4, 2.85e–45.58e–4, 3.44e–4
Range 49 to <50 μg/m3≥10 μg/m3≥10 000 μg/m3-days
β4, SE−0.1317, 0.0393−0.2618, 0.0712−1.234, 0.4393−1.659, 0.6726−4.14e–5, 2.33e–5−4.75e–5, 3.89e–5
Range 5≥50 μg/m3Not applicableNot applicable
β5, SE0.00513, 0.005180.00483, 0.00856
  • * Adjusting for birth cohort and plant.

  • Beta coefficients are combined as follows to produce a HR at a given exposure x, where for any value (d)+, (d)+=0 if d<0 and (d)+=d if d ≥ 0: mean exposure: ln(HR)=β1x+β2(x–0.8)+3(x–1.6)+4(x–9.0)+5(x–50)+; maximum expo9+sure: ln(HR)=β1x+β2(x–1.0)+3(x–9.0)+4(x–10)+; cumulative exposure: ln(HR)=β1x+β2(x–200)+3(x–1000)+4(x–10 000)+.

  • Adjusting for birth cohort, plant, short-term work status and asbestos exposure.

  • § Adjusting for birth cohort, plant and short-term work status.