ORs (95% CIs) of works factors in 2000 for incident use of antidepressants between 2000 and 2003, men
| Work characteristic | Antidepressant (%) | Crude | Model 1* | Model 2† | Model 3‡ |
| High quantitative demands | 35 (5.5) | 2.06 (1.32 to 3.21) | 2.36 (1.47 to 3.81) | 2.46 (1.51 to 4.01) | 2.12 (1.29 to 3.48) |
| High work pace | 40 (3.9) | 1.27 (0.82 to 1.97) | 1.18 (0.75 to 1.86) | 1.16 (0.74 to 1.84) | 1.11 (0.70 to 1.77) |
| High emotional demands | 11 (3.9) | 1.16 (0.61 to 2.21) | 1.04 (0.53 to 2.03) | 1.07 (0.54 to 2.13) | 0.88 (0.43 to 1.77) |
| Low social support from colleagues | 63 (4.6) | 2.39 (1.45 to 3.94) | 2.48 (1.49 to 4.12) | 2.51 (1.50 to 4.18) | 2.28 (1.36 to 3.82) |
| Low social support from superiors | 69 (3.8) | 1.60 (0.91 to 2.83) | 1.66 (0.93 to 2.94) | 1.66 (0.93 to 2.95) | 1.48 (0.83 to 2.65) |
| Low sense of community | 19 (5.0) | 1.62 (0.96 to 2.73) | 1.66 (0.96 to 2.86) | 1.60 (0.92 to 2.79) | 1.28 (0.72 to 2.26) |
| Low meaning of work | 9 (6.9) | 2.22 (1.08 to 4.53) | 2.02 (0.97 to 4.22) | 2.16 (1.02 to 4.56) | 1.46 (0.66 to 3.21) |
| High physical demands | 7 (3.8) | 1.11 (0.51 to 2.45) | 0.89 (0.39 to 2.03) | 0.85 (0.37 to 1.99) | 0.66 (0.28 to 1.61) |
| Low opportunity for development | 14 (5.2) | 1.65 (0.91 to 2.97) | 1.58 (0.84 to 2.97) | 1.76 (0.93 to 3.33) | 1.48 (0.77 to 2.84) |
| Low variation of work | 25 (5.1) | 1.71 (1.06 to 2.76) | 1.55 (0.94 to 2.56) | 1.67 (1.00 to 2.78) | 1.55 (0.92 to 2.62) |
↵* Controlled for lifestyle, social relationships, co-morbidity and socio-demographic factors.
↵† Controlled for lifestyle, social relationships, co-morbidity and socio-demographic factors plus all other work environment factors.
↵‡ Controlled for lifestyle, social relationships, co-morbidity, socio-demographic factors and all other work environment factors plus Major Depression Inventory score.