HRs of first CHD event, by occupational class
| EGP class | No of events | Age-adjusted HR (95% CI) | MRF adjusted* | MRF and JS adjusted† | ||
| HR (95% CI) | Decrease in HR§ (%) | HR (95% CI) | Decrease in HR§ (%) | |||
| Administrators and professionals | 13 | 1.56 (0.6 to 4.0) | 1.55 (0.6 to 4.0) | 1.5 | 1.58 (0.6 to 4.1) | −2.7 |
| Non-manual workers | 7 | Ref | Ref | – | Ref | – |
| Manual workers | 13 | 1.49 (0.6 to 3.8) | 1.18 (0.5 to 3.0) | 57.8 | 1.12 (0.4 to 2.9) | 71.4 |
| Self-employed | 15 | 2.28 (0.9 to 5.7) | 2.38 (1.0 to 6.0) | −5.3 | 2.45 (1.0 to 6.2) | −8.9 |
| p Value‡ | – | 0.35 | 0.20 | 0.15 | ||
Results are based on CHD-free subjects, currently employed and with valid data on physical activity and job stress (N=1441). Age-adjusted HRs are the reference levels used to estimate decreases in MRF-adjusted and MRF plus job strain-adjusted HRs.
* MRF, multiple risk factors (age, systolic blood pressure, total cholesterol, HDL-cholesterol, current cigarette smokers, diabetes mellitus, alcohol intake, sport physical activity index).
† Multivariate model including MRF and job strain (PJD/DL ratio, dichotomised at the median).
‡ Heterogeneity, χ2 test p value.
§ On the logarithmic scale, from the age-adjusted model.
CHD, coronary heart disease; DL, decision latitude; EGP, Erikson–Goldthorpe–Portocarero class scheme; PJD, psychological job demand.