ORs and 95% CI for composite binary indices of occupational exposure to medium or high levels of selected substances, postmenopausal breast cancer, Montreal, Canada, 1996–7
| Substance | Non-substantial exposure* | Substantial exposure* | ||||||||||
| Exposed cases | Exposed controls | Age-adjusted | Fully adjusted† | Exposed cases | Exposed controls | Age-adjusted | Fully adjusted† | |||||
| (n) | (n) | OR | 95% CI | OR | 95% CI | (n) | (n) | OR | 95% CI | OR | 95% CI | |
| Acrylic fibres | 15 | 7 | 2.35 | 0.95 to 5.83 | 4.01 | 1.32 to 12.20 | 0 | 2 | — | — | — | — |
| Aliphatic aldehydes | 97 | 104 | 1.08 | 0.79 to 1.47 | 0.99 | 0.69 to 1.43 | 7 | 5 | 1.73 | 0.54 to 5.50 | 1.16 | 0.32 to 4.18 |
| Carbon monoxide | 85 | 82 | 1.15 | 0.82 to 1.60 | 1.10 | 0.72 to 1.67 | 0 | 1 | — | — | — | — |
| Inks | 12 | 10 | 1.31 | (0.56 to 3.06) | 1.89 | 0.67 to 5.33 | 3 | 3 | 0.94 | 0.19 to 4.71 | 1.29 | 0.21 to 7.99 |
| MAHs | 10 | 8 | 1.28 | 0.50 to 3.28 | 1.49 | 0.53 to 4.15 | 9 | 9 | 1.06 | 0.41 to 2.69 | 1.17 | 0.42 to 3.29 |
| Nylon fibres | 38 | 34 | 1.24 | 0.76 to 2.00 | 1.47 | 0.84 to 2.57 | 3 | 3 | 1.08 | 0.21 to 5.41 | 1.38 | 0.26 to 7.35 |
| PAHs from any source | 34 | 32 | 1.13 | 0.69 to 1.87 | 1.38 | 0.77 to 2.46 | 9 | 9 | 1.08 | 0.42 to 2.76 | 0.80 | 0.27 to 2.36 |
| PAHs from petroleum | 21 | 14 | 1.53 | 0.76 to 3.05 | 2.08 | 0.96 to 4.53 | 7 | 6 | 1.24 | 0.41 to 3.72 | 1.23 | 0.33 to 4.54 |
| Polyester fibres | 38 | 52 | 0.80 | 0.82 to 1.24 | 0.85 | 0.51 to 1.42 | 5 | 5 | 1.12 | 0.32 to 3.91 | 1.43 | 0.38 to 5.46 |
| Rayon fibres | 22 | 21 | 1.12 | 0.61 to 2.07 | 1.85 | 0.86 to 3.97 | 2 | 1 | 2.35 | 0.21 to 26.22 | 2.53 | 0.21 to 30.02 |
| Synthetic fibres | 63 | 69 | 1.01 | 0.70 to 1.45 | 1.14 | 0.74 to 1.76 | 10 | 14 | 0.76 | 0.33 to 1.73 | 0.93 | 0.36 to 2.41 |
| Wool fibres | 42 | 46 | 1.03 | 0.67 to 1.60 | 1.14 | 0.69 to 1.91 | 6 | 9 | 0.77 | 0.27 to 2.18 | 1.07 | 0.35 to 3.28 |
↵* Substantial exposure, ≥5 years of exposure at medium or high levels of intensity; non-substantial exposure, <5 years of exposure at medium or high levels of intensity, but still ≥5 years of exposure at any intensity.
↵† Adjusted for age, family history, age at oophorectomy, education, ethnicity, age at menarche, oral contraceptive use, duration of hormone replacement therapy use, total duration of breastfeeding, smoking status, alcohol consumption status, body mass index, age at first full-term pregnancy (≥35 weeks) and proxy respondent status.
MAHs, monoaromatic hydrocarbons; PAHs, polycyclic aromatic hydrocarbons.