Systemic sclerosis×exposure, systemic sclerosis×sector of activity and systemic sclerosis×occupation associations generating a signal with the PRR pharmacosurveillance method
| Systemic sclerosis cases | ||||
| No. of cases | No. of centres | Years of signal | ||
| Exposure (INRS/CNAM code) | ||||
| 31160 | Silica | 38 | 18 | 2002–2007 |
| 22224 | Trichloroethylene | 4 | 4 | 2003–2007 |
| 31146 | Hard metal dusts | 3 | 2 | 2006–2007 |
| 35110 | Solvents | 21 | 10 | 2003–2007 |
| 36R00 | Pesticides | 3 | 3 | 2007 |
| 48000 | Temperature conditions | 5 | 5 | 2006–2007 |
| 49000 | Vibrations | 3 | 3 | 2007 |
| Sector of activity (NAF code) | ||||
| 251 | Rubber industry | 3 | 3 | 2007 |
| 453F | Installation of heating and air conditioning equipment | 3 | 3 | 2005–2007 |
| 452B | Construction of miscellaneous buildings | 6 | 6 | 2003– |
| 502Z | Vehicle repair and maintenance | 4 | 4 | 2006 |
| Occupation (CITP88 code) | ||||
| 321 | Life sciences and health technicians | 3 | 2 | 2007 |
| 821 | Machine operators, mineral and metal processing | 4 | 4 | 2005–2007 |
| 823 | Machine operators, manufacture of rubber and plastic products | 6 | 5 | 2003–2007 |
| 914 | Building caretakers, window and related cleaners | 4 | 4 | 2007 |
| 932 | Labourers in manufacturing industries | 3 | 3 | 2006 |
| 7122 | Masons | 7 | 7 | 2003–2007 |
| 7136 | Plumbers and pipe-fitters | 4 | 4 | 2003–2005 |
CNAM , Caisse Nationale d'Assurance Maladie; INRS, Institut National de Recherche et Sécurité; NAF, Nomenclature des Activités Françaises; PRR, proportional reporting ratios. Data are from the 30 university hospital centres. Sample includes all occupational health reports. No. of centres, number of occupational disease consultation centres which supplied the reports; Years of signal, years when the emerging signal was reported.