Annual variation in numbers of preselected disease–exposure pairs in the 30 university hospital centres
| Diseases (ICD-10 codes) | Exposures | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | p Value* |
| No. of persons followed | 6134 | 6438 | 6967 | 6799 | 7034 | 7447 | ||
| Primary malignant neoplasms of the respiratory tract (C34–C39) | Asbestos and other inorganic substances | 229 | 289 | 289 | 299 | 453 | 549 | 0.00 |
| Primary malignant neoplasms of the respiratory tract (C34–C39) | Other chemical products | 13 | 23 | 20 | 17 | 26 | 45 | 0.00 |
| Mesothelioma (C45) | Asbestos and other inorganic substances | 63 | 68 | 87 | 76 | 99 | 94 | 0.06 |
| Pleural plaque (J92) | Asbestos and other inorganic substances | 865 | 801 | 1109 | 1004 | 985 | 804 | 0.00 |
| Mood (affective) disorders (F30–F39) and adjustment disorders, neurotic, stress-related and somatoform disorders (F40–F48, T74) | Mental exposures and organisational stress | 631 | 881 | 1151 | 1306 | 1466 | 1614 | 0.00 |
| Disorders of the cervical spine (M4712, M4822, M50, M500-M509, M530, M531, M5310, M5312, M5313, M5412, M542, M5422, M5423, M5429, M5482) | Physical workload, manual handling, manipulation and postural demands | 22 | 37 | 44 | 48 | 29 | 35 | 0,97 |
| Disorders of the thoracic, lumbar and sacral spine (M4316, M4327, M4795, M4806, M4855, M510, M511, M5324, M5338, M5385, M5395, M54, M5416, M543, M5430, M5436, M5437, M5439, M544, M5385, M5446, M5447, M5449, M545, M5450, M5456, M5457, M5459, M546, M5465, M5466, M5484, M5485, M5486, M5488) | Physical workload, manual handling, manipulation and postural demands | 237 | 253 | 294 | 240 | 239 | 286 | 0.22 |
| Synovitis, tenosynovitis and other disorders of shoulder or elbow tendons (M75, M70, M77) | Physical workload, manual handling, manipulation and postural demands | 264 | 297 | 295 | 361 | 322 | 408 | 0.00 |
| Carpal tunnel syndrome (G50–G59) | Physical workload, manual handling, manipulation and postural demands | 174 | 169 | 168 | 198 | 189 | 202 | 0.93 |
| Asthma (J45-J46) | Organic substances (vegetable and animal) | 192 | 147 | 173 | 138 | 129 | 110 | 0.00 |
| Asthma (J45–J46) | Cleaning products | 20 | 19 | 22 | 27 | 23 | 24 | 0.80 |
| Asthma (J45–J46) | Cosmetics | 36 | 39 | 43 | 50 | 39 | 34 | 0.33 |
| Asthma (J45–J46) | Other chemical products | 163 | 145 | 121 | 138 | 107 | 68 | 0.00 |
| Rhinitis, rhinopharyngitis (J30–J31) | Organic substances (animal and vegetable) | 105 | 107 | 106 | 87 | 61 | 83 | 0.00 |
| Rhinitis, rhinopharyngitis (J30–J31) | Cosmetics | 23 | 28 | 23 | 30 | 22 | 23 | 0.32 |
| Rhinitis, rhinopharyngitis (J30–J31) | Other chemical products | 38 | 38 | 25 | 31 | 20 | 26 | 0.00 |
| Dermatitis (allergic, irritant, other) (L20–L30) | Organic substances (animal and vegetable) | 99 | 129 | 124 | 121 | 112 | 114 | 0.18 |
| Dermatitis (allergic, irritant, other) (L20–L30) | Cleaning products | 151 | 155 | 151 | 143 | 157 | 133 | 0.01 |
| Dermatitis (allergic, irritant, other) (L20–L30) | Cosmetics | 92 | 94 | 87 | 97 | 113 | 126 | 0.17 |
| Dermatitis (allergic, irritant, other) (L20–L30) | Other chemical products | 259 | 259 | 250 | 218 | 233 | 213 | 0.00 |
| Primary or presumed primary malignant neoplasms of lymphoid, haematopoietic and related tissue (C81–C96) | Benzene and other chemical products | 16 | 19 | 19 | 28 | 27 | 39 | 0.00 |
↵* χ2 test for trend (Armitage).