Table 3

Associations between atopic outcomes and home proximity to a main road by age group

2–6 years7–15 years16+ years
No (%)Adjusted OR* (95% CI)p Value†No (%)Adjusted OR* (95% CI)p Value†No (%)Adjusted OR* (95% CI)p Value†
High HDM IgE
⩽150 mnanana136 (26.2)0.99 (0.77 to 1.26)0.911856 (19.4)1.02 (0.96 to 1.09)0.49
>150 m277 (26.6)13562 (18.9)1
Bands of distance
    <30 mnanana27 (27.6)1.18 (0.64 to 2.17)0.54354 (18.1)0.88 (0.74 to 1.03)0.18
    30–60 m22 (32.4)1.47 (0.75 to 2.85)285 (18.7)0.94 (0.79 to 1.12)
    60–90 m22 (22.0)0.86 (0.46 to 1.59)414 (21.2)1.06 (091 to 1.24)
    90–120 m38 (27.1)1.18 (0.65 to 2.17)399 (18.8)0.93 (0.80 to 1.09)
    120–150 m27 (23.9)1404 (20.2)1
Diagnosed hay fever
⩽150 m40 (3.7)0.81 (0.56 to 1.17)0.26256 (13.2)1.05 (0.89 to 1.23)0.662022 (14.4)1.01 (0.95 to 1.07)0.83
>150 m106 (4.4)1519 (12.7)13946 (14.4)1
Bands of distance
    <30 m53 (14.6)1.14 (0.72 to 1.79)0.33378 (13.4)0.96 (0.82 to 1.11)0.93
    30–60 m43 (15.1)1.13 (0.71 to 1.78)343 (15.2)1.13 (0.96 to 1.32)
    60–90 m52 (12.9)1.01 (0.66 to 1.56)438 (15.2)1.10 (0.94 to 1.28)
    90–120 m55 (11.7)0.88 (0.57 to 1.35)453 (14.3)1.03 (0.89 to 1.20)
    120–150 m53 (12.9)1410 (14.2)1
Diagnosed eczema
⩽150 m294 (27.0)0.97 (0.83 to 1.14)0.73423 (21.9)0.92 (0.81 to 1.05)0.201828 (13.0)1.03 (0.97 to 1.09)0.35
>150 m677 (28.1)1959 (23.5)13517 (12.8)1
Bands of distance
    <30 m60 (31.9)1.32 (0.84 to 2.08)0.2767 (18.4)0.78 (0.55 to 1.13)0.53350 (12.5)0.90 (0.77 to 1.05)0.71
    30–60 m35 (25.4)1.02 (0.63 to 1.64)64 (22.6)1.03 (0.71 to 1.51)311 (13.7)1.05 (0.90 to 1.23)
    60–90 m69 (27.7)1.15 (0.77 to 1.73)108 (26.7)1.28 (0.92 to 1.77)386 (13.4)0.99 (0.85 to 1.16)
    90–120 m67 (25.8)1.05 (0.69 to 1.58)93 (19.8)0.87 (0.61 to 1.23)388 (12.3)0.90 (0.77 to 1.05)
    120–150 m63 (25.2)191 (22.1)1393 (13.6)1
  • *OR, odds ratios adjusted for sex and Townsend quintiles and, in adults, also for groups of age and smoking status.

  • †p Value of Wald test for association in ⩽150 m versus 150 m effects and for trend in bands of distance effects.

  • ‡Estimates for 30 m bands of distance in 2–6-year age group not included because of small numbers.

  • HDM IgE, immunoglobulin E against house dustmites; na, not available.