Table 4 Association between exposure to high-strain or active job during three study phases and verbal meaning and phonemic fluency change score (belonging to the worst quintile) between phases 5 and 7 (odds ratios (ORs) and 95% CI)
Verbal meaning/Mill Hill (the worst quintile)Phonemic fluency change (the worst quintile)
Adjusted for age and sexAdjusted for age, sex and employment gradeAdjusted for age and sexAdjusted for age, sex and employment grade
No/casesOR (95% CI)OR (95% CI)No/casesOR (95% CI)OR (95% CI)
High-strain job over three phases
No exposure2503/505112485/52211
1 exposure1011/2151.08 (0.90 to 1.29)1.03 (0.86 to 1.24)1006/2151.02 (0.85 to 1.22)1.05 (0.87 to 1.26)
2 exposures453/951.06 (0.82 to 1.36)1.02 (0.80 to 1.31)452/940.98 (0.77 to 1.26)1.02 (0.79 to 1.31)
3 exposures161/431.48 (1.03 to 2.13)1.42 (0.98 to 2.05)160/411.29 (0.89 to 1.87)1.34 (0.92 to 1.95)
p value for trend0.7950.1880.4320.246
Active job over three phases
No exposure1796/414111785/35811
1 exposure934/1840.81 (0.78 to 0.99)0.90 (0.73 to 1.11)927/1991.12 (0.92 to 1.37)1.10 (0.86 to 1.35)
2 exposures715/1210.68 (0.53 to 0.86)0.79 (0.61 to 1.00)710/1551.14 (0.92 to 1.42)1.09 (0.86 to 1.38)
3 exposures682/1390.83 (0.67 to 1.04)1.00 (0.77 to 1.28)681/1601.25 (1.00 to 1.55)1.18 (0.90 to 1.51)
p value for trend0.0120.5240.0380.197
  • No exposure is the reference category.

  • All models are also adjusted for time interval between phases 5 and 7.