Table 4 Adjusted risk estimates for squamous upper aero-digestive cancers among males in association with wood dust exposure, Roswell Park Cancer Institute, 1982–1998
Wood dust exposureCases,n (%)Controls,n (%)Adjusted OR,OR (95% CI)p Trend
All squamous upper aero-digestive cancers* (cases = 725 and controls = 1522)
    Never exposed519 (71.6)1153 (75.8)Ref
    Occasionally exposed129 (17.8)262 (17.2)1.01 (0.77 to 1.31)0.20
    Regularly exposed77 (10.6)107 (7.0)1.33 (0.93 to 1.90)
Squamous cell carcinoma of the oral cavity and oropharynx† (cases = 218 and controls = 1522)
    Never exposed169 (77.5)1153 (75.8)Ref
    Occasionally exposed28 (12.8)262 (17.2)0.68 (0.44 to 1.06)0.89
    Regularly exposed21 (9.6)107 (7.0)1.27 (0.76 to 2.14)
Squamous cell carcinoma of the nasal cavity and naso- pharynx and hypopharynx‡ (cases = 67 and controls = 1522)
    Never exposed42 (62.7)1153 (75.8)Ref
    Occasionally exposed17 (25.4)262 (17.2)1.83 (1.01 to 3.33)0.02
    Regularly exposed8 (11.9)107 (7.0)2.15 (0.98 to 4.72)
Squamous cell carcinoma of the larynx§ (cases = 121 and controls = 1522)
    Never exposed85 (70.2)1153 (75.8)Ref
    Occasionally exposed21 (17.4)262 (17.2)0.75 (0.42 to 1.35)0.54
    Regularly exposed15 (12.4)107 (7.0)1.50 (0.79 to 2.83)
Squamous cell carcinoma of the lung and trachea¶ (cases = 266 and controls = 1522)
    Never exposed177 (66.5)1153 (75.8)Ref
    Occasionally exposed57 (21.4)262 (17.2)1.43 (0.97 to 2.10)0.003
    Regularly exposed32 (12.0)107 (7.0)1.93 (1.18 to 3.17)
Squamous cell carcinoma of the oesophagus** (cases = 53 and controls = 1522)
    Never exposed46 (86.8)1153 (75.8)Ref
    Occasionally exposed6 (11.3)262 (17.2)0.61 (0.25 to 1.49)0.09
    Regularly exposed1 (1.9)107 (7.0)0.25 (0.03 to 1.81)
  • OR, odds ratio.

  • *Adjusted for age, education, pack years of smoking, body mass index, family income, smoking status and year of enrolment.

  • †Adjusted for age, pack years of smoking, body mass index, smoking status, alcoholic drinks per week, education and year of enrolment.

  • ‡Adjusted for age, education, pack years of smoking and year of enrolment.

  • §Adjusted for age, education, pack years of smoking, smoking status and year of enrolment.

  • ¶Adjusted for age, education, pack years of smoking, body mass index, smoking status, family income and year of enrolment.

  • **Adjusted for age, pack years of smoking, and year of enrolment.