Table 3 Adjusted risk estimates for upper aero-digestive cancers among males in association with the cumulative measure of intensity and duration of wood dust exposure, Roswell Park Cancer Institute, 1982–1998
Wood dust exposureCases,n (%)Controls,n (%)Adjusted OR,OR (95% CI)p Trend
All upper aero-digestive cancers* (cases = 1491 and controls = 1510)
    Never exposed1085 (72.8)1153 (76.4)Ref
    Moderate exposure group339 (22.7)318 (21.1)1.08 (0.89 to 1.31)0.04
    High exposure group67 (4.5)39 (2.6)1.69 (1.09 to 2.64)
Nasal cavity and nasopharyngeal and hypopharyngeal cancers† (cases = 89 and controls = 1510)
    Never exposed60 (67.4)1153 (76.4)Ref
    Moderate exposure group26 (29.2)318 (21.1)1.50 (0.91 to 2.46)0.14
    High exposure group3 (3.4)39 (2.6)1.35 (0.40 to 4.61)
Laryngeal cancers‡ (cases = 122 and controls = 1510)
    Never exposed86 (70.5)1153 (76.4)Ref
    Moderate exposure group27 (22.1)318 (21.1)0.78 (0.46 to 1.34)0.61
    High exposure group9 (7.4)39 (2.6)2.08 (0.87 to 4.96)
Lung and tracheal cancers§ (cases = 788 and controls = 1510)
    Never exposed557 (70.7)1153 (76.4)Ref
    Moderate exposure group187 (23.7)318 (21.1)1.12 (0.89 to 1.42)0.009
    High exposure group44 (5.6)39 (2.6)2.15 (1.31 to 3.56)

  • OR, odds ratio. Moderate exposure group: occasional exposure or regular exposure for <20 years. High exposure group: regular exposure for ⩾20 years.

  • *Adjusted for age, pack years of smoking, body mass index, family income and year of enrolment.

  • †Adjusted for age, education, pack years of smoking and year of enrolment.

  • ‡Adjusted for age, education, pack years of smoking, alcoholic drinks per week, family income and year of enrolment.

  • §Adjusted for age, education, pack years of smoking, body mass index, asbestos, family income and year of enrolment.