Mutually adjusted ORs for farmer’s lung among farmers in the Agricultural Health Study, 1993–7; results from expanded models including individual pesticides
| Exposure | Farmer’s lung | OR* (95% CI) | |
|---|---|---|---|
| Cases (n = 395) | Controls (n = 16 563) | ||
| n (%) | n (%) | ||
| *ORs adjusted for age, state, smoking status and cigarettes per day and all other exposures. | |||
| †Grain, animal and other farm exposures are based on current activities. | |||
| ‡Pesticide group variables are based on lifetime exposure. | |||
| Grain group† | |||
| Grind feed | 249 (63) | 7934 (48) | 1.13 (0.86 to 1.50) |
| Grow grain | 379 (96) | 14 455 (87) | 0.80 (0.46 to 1.37) |
| Handle grain | 356 (90) | 12 234 (74) | 1.13 (0.78 to 1.64) |
| Handle hay | 282 (71) | 9796 (59) | 1.16 (0.88 to 1.53) |
| Handle silage | 143 (36) | 3534 (21) | 1.44 (1.12 to 1.87) |
| Animal group† | |||
| Beef cattle | 1.04 (0.80 to 1.35) | ||
| Dairy cattle | 33 (8) | 956 (6) | 1.15 (0.76 to 1.72) |
| Hogs | 163 (41) | 5910 (36) | 0.89 (0.66 to 1.20) |
| Poultry houses | 14 (4) | 563 (3) | 1.42 (0.83 to 2.42) |
| Swine areas | 141 (36) | 4968 (30) | 0.90 (0.67 to 1.22) |
| Veterinary procedures | 272 (69) | 9187 (56) | 0.93 (0.73 to 1.19) |
| Other exposures† | |||
| Diesel tractors | 388 (98) | 15 414 (93) | 1.45 (0.74 to 2.82) |
| Drive combines | 369 (93) | 13 479 (81) | 1.26 (0.83 to 1.93) |
| Grind metal | 316 (80) | 11 596 (70) | 0.98 (0.73 to 1.32) |
| Solvents to clean | 237 (60) | 8418 (51) | 1.16 (0.93 to 1.44) |
| Welding | 315 (80) | 10 911 (66) | 1.32 (0.99 to 1.76) |
| Pesticide group‡ | |||
| High pesticide exposure event | 104 (26) | 2439 (15) | 1.71 (1.35 to 2.17) |
| Organophosphate insecticides | 383 (97) | 15 283 (92) | 1.26 (0.72 to 2.18) |
| Permethrin insecticides | 120 (30) | 3857 (23) | 1.16 (0.91 to 1.48) |
| Phenoxy herbicides | 363 (92) | 13 431 (81) | 1.12 (0.77 to 1.64) |
| Triazine herbicides | 367 (93) | 13 357 (81) | 1.14 (0.76 to 1.70) |
| Organochlorines‡ | |||
| Aldrin | 148 (38) | 3511 (21) | 1.05 (0.79 to 1.39) |
| Chlordane | 133 (34) | 4516 (27) | 0.96 (0.74 to 1.25) |
| DDT | 153 (39) | 4469 (27) | 1.25 (0.95 to 1.65) |
| Dieldrin | 55 (14) | 1303 (8) | 0.86 (0.61 to 1.21) |
| Heptachlor | 141 (36) | 3012 (18) | 1.15 (0.87 to 1.52) |
| Lindane | 128 (32) | 3334 (20) | 1.25 (0.98 to 1.60) |
| Toxaphene | 68 (17) | 2436 (15) | 0.86 (0.63 to 1.18) |
| Carbamates‡ | |||
| Aldicarb | 25 (6) | 1655 (10) | 1.65 (1.04 to 2.61) |
| Benomyl | 10 (3) | 1610 (10) | 0.60 (0.33 to 1.07) |
| Carbaryl | 232 (59) | 9494 (57) | 1.19 (0.94 to 1.49) |
| Carbofuran | 153 (39) | 4672 (28) | 1.12 (0.89 to 1.40) |