Table 2

 Weekly working hours, shift work, standing and risk of preterm delivery

First author (year)Numbers in analysisRR (95% CI)ExposureHigher potential forIncomplete reportingPooled in meta-analysis
ComparisonTimingBiasConfounding
h/d, hours per day; h/wk, hours per week.
RR is used generically to encompass a variety of published effect measures (odds ratios, incidence density ratios, hazard ratios and so on).
*Excluded from sensitivity analysis.
†Effective response rate <50%.
‡Not pooled as a standard error could not be derived from the published data.
§Second trimester chosen for meta-analysis (being the most comparable with other studies).
Weekly working hours
    Cohort studies
        Brink-Henriksen T (1995)109271.87 (0.78 to 4.16)⩾45 vs <30 h/wk16 weeksNoNoNoYes
        Hickey CA (1995)171830.68 (0.12 to 2.7)>40 vs 1–20 h/wk24–26 weeksNoNoYesYes*
        Pompeii LA (2005)3810370.6 (0.4 to 0.9)>46 vs 35–45 h/wkTrimester 1NoNoNoNo
        Pompeii LA (2005)3810370.4 (0.2 to 0.8)>46 vs 35–45 h/wkTrimester 2NoNoNoNo
        Pompeii LA (2005)3810370.3 (0.1 to 0.7)>46 vs 35–45 h/wkTrimester 3NoNoNoNo
        Tuntiseranee P (1998)528861.6 (0.8 to 3.3)⩾61 vs ⩽50 h/wk15–28 weeksNoNoNoNo
    Case–control studies
        Luke B† (1995)2414701.6 (1.1 to 2.2)>36 vs ⩽36 h/wkNot statedNoNoNoNo
        Saurel-Cubizolles MJ (2004)4520621.33 (1.1 to 1.6)⩾43 vs 30–39 h/wkTrimester 1NoNoYesYes*
    Cross-sectional studies
        Bodin L (1999)816851.3 (0.6 to 2.7)⩾36 vs 21–35 h/wkTrimester 2NoNoNoNo
        Ceron-Mireles P (1996)1124291.21 (0.9 to 1.62)>50 vs 3–25 h/wkNot statedNoNoNoYes
        Fortier I (1995)1318331.14 (0.71 to 1.82)⩾40 vs <30 h/wkNot statedNoNoNoYes
        Klebanoff MA (1990)209891.2 (0.8 to 1.7)Residents (>100 h) vs othersAnyNoNoNoNo
        Mamelle N (1984)2719281.7 (1.1 to 2.5)>41 vs ⩽40 h/wkNot statedNoYesYesYes*
        McDonald AD (1988)29227611.34, p<0.05⩾46 vs <46 h/wkNot statedNoNoNoNo‡
        Peoples-Sheps MD (1991)3618531.1 (0.7 to 1.8)⩾40 vs 1–20 h/wkNot statedNoNoNoYes
        Saurel-Cubizolles MJ (1987)4322450.59 (0.21 to 1.37)⩾42 vs <42 h/wkTrimester 1NoYesYesNo
        Saurel-Cubizolles MJ (1991)448731.0 (0.4 to 2.5)>45 vs ⩽45 h/wkNot statedNoNoYesNo
        Savitz DA (1996)4610151.1 (0.8 to 1.5)⩾40 vs no paid work5 monthsNoNoNoYes
Shift work
    Cohort studies
        Misra DP (1998)3211661.0 (0.59 to 1.69)Shifts vs noneTrimesters 1 and 2NoNoNoYes
        Pompeii LA (2005)3817961.5 (1.0 to 2.1)Regular night work (yes vs no)Trimester 1NoNoNo
        Pompeii LA (2005)3817961.6 (1.0 to 2.8)Regular night work (yes vs no)Trimester 2NoNoNoYes§
        Pompeii LA (2005)3817961.8 (0.8 to 3.4)Regular night work (yes vs no)Trimester 3NoNoNo
        Stinson JC† (2003)493591.8 (0.93 to 3.53)Night vs day22–26 weeksNoNoNoYes
        Xu X (1994)558872.0 (1.1 to 3.4)Rotating shift work (yes vs no)Not statedNoNoNoYes
        Zhu JL (2004)56356620.97 (0.8 to 1.17)Rotating shift work vs daytime workTrimesters 1 and 2NoNoNoYes
    Case–control studies
        Hartikainen-Sorri AL (1989)153580.86 (0.51 to 1.45)Shift work (yes vs no)Not statedNoYesYesYes*
        Luke B† (1995)2414701.5 (1.1 to 2.1)Evening/night vs dayNot statedYesNoNoYes*
        Saurel-Cubizolles MJ (2004)4563090.97 (0.8 to 1.1)Shift work (yes vs no)Trimester 1NoNoYesYes
    Cross-sectional studies
        Bodin L (1999)816855.6 (1.9 to 16.4)Night vs dayTrimester 2NoNoNoYes
        Fortier I (1995)1341181.03 (0.72 to 1.48)Shift work vs day onlyNot statedNoNoNoYes
        Mamelle N (1984)2719281.6 (1.0 to 2.5)Shift and night work vs noneNot statedNoYesYesYes*
        McDonald AD (1988)29227611.18, p>0.05Changing shift vs notNot statedNoNoNoNo‡
        Nurminen T (1989)34Unclear0.9 (0.7 to 1.1)Shift work (yes vs no)Not statedNoNoNoYes
        Saurel-Cubizolles MJ (1987)4322610.8 (0.16 to 2.51)Night vs dayTrimester 1NoYesYesYes*
Standing
    Cohort studies
        Brink-Henriksen T (1995)1042591.2 (0.6 to 2.4)>5 vs 0–2 h/d16 weeksNoNoNoYes
        Hickey CA (1995)176121.11 (0.61 to 2.11)>3 vs ⩽3 h/d24–26 weeksNoNoYesYes*
        Klebanoff MA (1990)2171011.31 (1.01 to 1.71)⩾8 vs 0 h/d1–5 monthsNoNoNoYes
        Launer LJ (1990)2341681.56 (1.04 to 2.6)Standing vs sittingNot statedNoNoNoNo
        Magann EF (2005)264851.64 (0.88 to 3.06)⩾4 vs <4 h/dTrimester 1NoNoNoNo
        Misra DP (1998)3211661.05 (0.63 to 1.71)⩾3 vs <3 h/dTrimesters 1 and 2NoYesNoYes*
        Newman RB (2001)3312181.69 (1.2 to 2.38)>3 vs ⩽3 h/d22–24 weeksNoNoNoYes
        Pompeii LA (2005)389771.2 (0.9 to 1.7)>30 vs 6–15 h/wkTrimester 1NoNoYes
        Pompeii LA (2005)389770.9 (0.6 to 1.2)>30 vs 6–15 h/wkTrimester 2NoNoYesYes§
        Pompeii LA (2005)389771.3 (0.8 to 2.3)>30 vs 6–15 h/wkTrimester 3NoNoYes
        Teitelman AM (1990)517082.72 (1.24 to 5.95)Standing still >3 h/d vs continuous active motionTrimester 1 (mostly)NoNoNoYes
        Tuntiseranee P (1998)5211210.9 (0.3 to 2.3)⩾5 vs ⩽4 h/d15–28 weeksNoNoNoNo
    Case–control studies
        Berkowitz GS (1983)71861.36 (0.73 to 2.55)Most/all of the time vs none/little of the timeNot statedNoYesNoYes*
        Hartikainen-Sorri AL (1989)153581.16 (0.71 to 1.9)Standing-moving vs notNot statedNoYesNoNo
        Luke B† (1995)2414702.42 (1.37 to 4.62)>4 vs <4 h/dNot statedYesNoNoNo
        Saurel-Cubizolles MJ (2004)4548101.26 (1.1 to 1.5)>6 vs <2 h/dTrimester 1NoNoYesYes*
    Cross-sectional studies
        Ceron-Mireles P (1996)1124291.16 (0.89 to 1.51)>7 vs ⩽7 h/dNot statedNoNoNoNo
        Fortier I (1995)1335020.88 (0.59 to 1.33)⩾6 vs <3 h/dNot statedNoNoNoYes
        Mamelle N (1984)2719281.6 (1.0 to 1.9)⩾3 vs <3 h/dNot statedNoYesYesYes*
        McDonald AD (1988)29227611.07, p>0.05Standing ⩾8 vs <8 h/dNot statedNoNoNo‡No
        Saurel-Cubizolles MJ (1987)4322691.29 (0.85 to 1.94)Standing (yes vs no)Trimester 1NoYesYesNo
        Saurel-Cubizolles MJ (1991)448741.59 (0.82 to 3.19)Standing (often/always vs none/sometimes)Not statedNoNoYesYes*