Standardised incidence ratio (SIR) of lung cancer and mesotheliomas in 1971–95 by gender and cumulative exposure (CE) to eight organic dusts among economically active Finns born 1906–45
| Agent | CE class | Lung cancer | Mesotheliomas | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Men | Women | Men | Women | ||||||||||
| O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | ||
| O, observed number of cases; CI, confidence interval; SIRs adjusted for age and social class, exposure lag period 20 years. | |||||||||||||
| Wood dust | None (0) | 27309 | 1.00 | 0.98–1.01 | 3446 | 1.00 | 0.97–1.03 | 408 | 1.01 | 0.91–1.11 | 135 | 0.97 | 0.81–1.14 |
| Low (<3 mg/m3-year) | 936 | 1.11 | 1.04–1.18 | 21 | 0.92 | 0.57–1.41 | 12 | 0.83 | 0.43–1.46 | 4 | 4.57 | 1.25–11.7 | |
| Medium (3–50 mg/m3-year) | 1784 | 1.02 | 0.97–1.06 | 48 | 1.03 | 0.76–1.37 | 28 | 0.98 | 0.65–1.41 | 4 | 2.10 | 0.57–5.37 | |
| High (>50 mg/m3-year) | 108 | 0.85 | 0.70–1.02 | 12 | 0.95 | 0.49–1.66 | 2 | 1.06 | 0.13–3.84 | 0 | 0.00 | 0.00–7.67 | |
| Pulp or paper dust | None (0) | 29933 | 1.00 | 0.99–1.01 | 3477 | 1.00 | 0.97–1.04 | 449 | 1.01 | 0.92–1.11 | 139 | 0.99 | 0.83–1.17 |
| Low (<10 mg/m3-year) | 102 | 0.82 | 0.67–1.00 | 25 | 0.97 | 0.62–1.43 | 0 | 0.00 | 0.00–1.42 | 3 | 2.97 | 0.61–8.67 | |
| Medium (10–15 mg/m3-year) | 100 | 0.82 | 0.66–0.99 | 23 | 0.71 | 0.45–1.07 | 1 | 0.43 | 0.01–2.38 | 1 | 0.80 | 0.02–4.44 | |
| High (>15 mg/m3-year) | 2 | 1.22 | 0.15–4.42 | 2 | 1.08 | 0.13–3.89 | 0 | 0.00 | 0.00–31.8 | 0 | 0.00 | 0.00–65.2 | |
| Flour dust | None (0) | 29944 | 1.00 | 0.99–1.01 | 3116 | 1.00 | 0.97–1.04 | 448 | 1.00 | 0.91–1.10 | 132 | 1.03 | 0.87–1.23 |
| Low (<5 mg/m3-year) | 54 | 0.86 | 0.65–1.13 | 350 | 0.97 | 0.87–1.07 | 0 | 0.00 | 0.00–3.13 | 10 | 0.78 | 0.37–1.43 | |
| Medium (5–50 mg/m3-year) | 50 | 0.89 | 0.66–1.18 | 17 | 0.68 | 0.40–1.10 | 1 | 0.83 | 0.02–4.60 | 0 | 0.00 | 0.00–3.55 | |
| High (>50 mg/m3-year) | 89 | 0.95 | 0.77–1.18 | 44 | 1.20 | 0.87–1.61 | 1 | 0.63 | 0.02–3.50 | 1 | 0.66 | 0.02–3.66 | |
| Plant dust | None (0) | 23211 | 1.03 | 1.02–1.05 | 2684 | 1.00 | 0.97–1.04 | 409 | 1.01 | 0.91–1.11 | 106 | 1.00 | 0.82–1.21 |
| Low (<10 mg/m3-year) | 2555 | 0.86 | 0.82–0.89 | 495 | 0.99 | 0.90–1.08 | 20 | 0.93 | 0.57–1.43 | 20 | 0.90 | 0.55–1.39 | |
| Medium (10–40 mg/m3-year) | 4340 | 0.93 | 0.90–0.96 | 347 | 0.98 | 0.88–1.09 | 21 | 0.98 | 0.60–1.49 | 17 | 1.16 | 0.68–1.86 | |
| High (>40 mg/m3-year) | 31 | 1.06 | 0.72–1.51 | 1 | 0.55 | 0.01–3.05 | 0 | 0.00 | 0.00–8.50 | 0 | 0.00 | 0.00–50.1 | |
| Textile dust | None (0) | 29867 | 1.00 | 0.99–1.01 | 3288 | 1.01 | 0.98–1.05 | 449 | 1.01 | 0.92–1.11 | 131 | 0.99 | 0.83–1.18 |
| Low (<5 mg/m3-year) | 162 | 1.08 | 0.92–1.26 | 95 | 0.99 | 0.80–1.21 | 0 | 0.00 | 0.00–1.43 | 4 | 1.15 | 0.31–2.94 | |
| Medium (5–20 mg/m3-year) | 82 | 0.87 | 0.69–1.08 | 125 | 0.79 | 0.66–0.95 | 1 | 0.61 | 0.02–3.42 | 4 | 0.62 | 0.17–1.59 | |
| High (>20 mg/m3-year) | 26 | 0.66 | 0.43–0.97 | 19 | 0.60 | 0.36–0.94 | 0 | 0.00 | 0.00–5.24 | 4 | 3.18 | 0.87–8.15 | |
| Leather dust | None (0) | 30069 | 1.00 | 0.99–1.01 | 3511 | 1.00 | 0.97–1.04 | 450 | 1.00 | 0.91–1.10 | 143 | 1.01 | 0.85–1.19 |
| Low (<5 mg/m3-year) | 47 | 0.85 | 0.62–1.13 | 12 | 0.66 | 0.34–1.15 | 0 | 0.00 | 0.00–4.04 | 0 | 0.00 | 0.00–5.14 | |
| Medium (5–20 mg/m3-year) | 20 | 0.88 | 0.54–1.36 | 4 | 0.90 | 0.24–2.30 | 0 | 0.00 | 0.00–8.58 | 0 | 0.00 | 0.00–19.4 | |
| High (>20 mg/m3-year) | 1 | 1.00 | 0.03–5.55 | 0 | 0.00 | 0.00–28.1 | 0 | 0.00 | 0.00–263 | 0 | 0.00 | 0.00–728 | |
| Animal dust | None (0) | 24237 | 1.03 | 1.01–1.04 | 3105 | 1.01 | 0.97–1.05 | 420 | 1.00 | 0.91–1.10 | 122 | 1.01 | 0.84–1.20 |
| Low (<0.5 mg/m3-year) | 4519 | 0.89 | 0.87–0.92 | 136 | 0.95 | 0.79–1.12 | 22 | 0.98 | 0.61–1.49 | 6 | 0.63 | 0.23–1.37 | |
| Medium (0.5–1.5 mg/m3-year) | 1321 | 0.92 | 0.87–0.97 | 284 | 0.93 | 0.83–1.05 | 8 | 0.99 | 0.43–1.96 | 15 | 1.21 | 0.68–2.00 | |
| High (>1.5 mg/m3-year) | 60 | 1.22 | 0.93–1.57 | 2 | 0.46 | 0.06–1.65 | 0 | 0.00 | 0.00–10.2 | 0 | 0.00 | 0.00–18.5 | |
| Synthetic polymer dust | None (0) | 29877 | 1.00 | 0.99–1.01 | 3392 | 1.01 | 0.98–1.04 | 448 | 1.00 | 0.91–1.10 | 138 | 1.01 | 0.85–1.20 |
| Low (<5 mg/m3-year) | 204 | 0.94 | 0.82–1.08 | 135 | 0.81 | 0.68–0.96 | 2 | 0.54 | 0.07–1.96 | 5 | 0.75 | 0.24–1.75 | |
| Medium (5–20 mg/m3-year) | 46 | 0.68 | 0.49–0.90 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 | |
| High (>20 mg/m3-year) | 10 | 1.23 | 0.59–2.26 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 | 0 | 0.00 | 0.00 | |