Table 2

‚ÄÉRevised SIGN grading system for recommendations

Recommendations
AAt least one meta-analysis, systematic review, or RCT rated as 1++, and directly applicable to the target population; or a systematic review of RCTs or a body of evidence consisting principally of studies rated as 1+, directly applicable to the target population, and showing overall consistency of results
BA body of evidence including studies rated as 2++, directly applicable to the target population, and showing overall consistency of results; or extrapolated evidence from studies rated as 1++ or 1+
CA body of evidence including studies rated as 2+, directly applicable to the target population and showing overall consistency of results; or extrapolated evidence from studies rated as 2++
DEvidence level 3 or 4; or extrapolated evidence from studies rated as 2+