Table 3

Pooled effect estimates for cough where n represents the number of studies and p values derive from the Q combinality test for homogeneity between study effect estimates

PollutantMethod of pooling or subgroupMultiplicative change in symptom odds per unit (μg.m−3) increase in pollutantExpected impact on symptom odds of a 50 μg.m−3 rise in pollutantQ test p valuen
Pooled effect estimate95% confidence interval
*Number greater than the total number of studies as some studies present results separately for symptomatic and non-symptomatic/asthmatic children.
PM2.5Overall pooled effect estimate
    Fixed effects model1.0051.0031.0071.28<0.0256
    Random effects model1.0101.0051.0161.64
PM10Overall pooled effect estimate
    Fixed effects model1.0000.9991.0011.00<0.00112
    Random effects model1.0041.0021.0061.2212
Subgroups based on outcome measures (fixed effects models)
    Symptom prevalence only1.0000.9991.0011.00<0.0018
Subgroups based on the population studied (fixed effects models)
    Asthmatic or symptomatic children1.0000.9991.0011.00<0.0019*
    Non-symptomatic children1.0021.0011.0041.11<0.0255*
Subgroups based on environmental conditions (fixed effects models)
    High ozone levels1.0101.0061.0141.64<0.0013
    High SO2 levels1.0011.0001.0021.05<0.0252
    High PM10 levels only1.0001.0001.0001.00<0.0018
Subgroups based on pollutant lag (fixed effects models)
    Same day or prior two days1.0000.9991.0011.00<0.0018
Subgroups based on analytical approach (fixed effects models)
    Use of a two-stage approach1.0051.0031.0071.28<0.0013
    Use of a population daily average outcome1.0000.9991.0011.00<0.0019
    Autocorrelation modelled using GEE1.0051.0041.0071.28<0.0016
    Autocorrelation not modelled using GEE1.0000.9991.0011.00<0.0016