Table 2

Factors affecting the amount of chemical that is absorbed through the skin

Exposure factors
Type of task
Area of skin exposed
Use of protective clothing
Concentration of the chemical
Hygiene: washing and wearing of contaminated clothing
Chemical factors
Molecular weight
Solubility in water
Solubility in oils
Presence of other chemicals
Skin factors
Skin thickness
Skin type and condition
Anatomical location of exposure
Temperature and humidity
Skin perfusion
Hairiness, pore density and sweating
Skin metabolism