Factors affecting the amount of chemical that is absorbed through the skin
| Exposure factors |
| Type of task |
| Duration |
| Area of skin exposed |
| Use of protective clothing |
| Concentration of the chemical |
| Hygiene: washing and wearing of contaminated clothing |
| Chemical factors |
| Molecular weight |
| Solubility in water |
| Solubility in oils |
| Structure |
| Irritancy |
| Presence of other chemicals |
| Skin factors |
| Skin thickness |
| Skin type and condition |
| Anatomical location of exposure |
| Temperature and humidity |
| Occlusion |
| Skin perfusion |
| Hairiness, pore density and sweating |
| Skin metabolism |