Parameter | Value |
---|---|

†δ and _{0}δ are parameters for a Weibull model, centred at age 55 years, describing the annual rate of mortality in the absence of exposure; values for _{1}δ and _{0}δ are specified such that simulations approximate the age specific cancer mortality rates in a large cohort of US workers._{1} | |

‡η and _{0}η are parameters for a Weibull model, centred at age 55 years, describing the rate of mortality due to causes other than the one under study._{1} | |

The exponential distribution, with mean and variance equal to 1, is denoted Exp(1). | |

Number of iterations of simulation | 100 |

Number of persons in study cohort | 25000 |

Age at entry, in years | 18+10(Exp(1)) |

Length of follow up, in years | 40-5(Exp(1)) |

Length of employment, in years | 25Exp(1) |

Baseline disease incidence rate, (δ)†_{0}, δ_{1} | −6.3, 5.7 |

Rate of censoring due to death from causes other than the one under study, (η)‡_{0}, η_{1} | −5.0, 5.0 |

Exposure effect (per 10 units exposure), e^{φ} | 1.50 |