Intra-individual changes in hyperintense spots on T2 weighted images over six years
| Proportion of “increased” | Age adjusted OR (95% CI)* | Multivariate adjusted OR (95% CI)† | Proportion of “at least 1 category increased” | Age adjusted OR (95% CI)* | Multivariate adjusted OR (95% CI)† | |
|---|---|---|---|---|---|---|
| *Exposure variable and age were included in the logistic regression model. | ||||||
| †Adding to variables in the age adjusted model, smoking (0, 1–20, >20 pack-years), alcohol intake (0, 1–50, >50 g ethanol/day), BMI, education level (at least high school, or less), shift work (yes or no), systolic blood pressure, and HDL cholesterol. | ||||||
| Reference | 40/324 (12.4%) | 1 | 1 | 20/324 (6.2%) | 1 | 1 |
| Ex-exposed | 19/125 (15.2%) | 1.24 (0.68 to 2.27) | 1.33 (0.70 to 2.54) | 13/125 (10.4%) | 1.74 (0.83 to 3.64) | 1.62 (0.74 to 3.59) |
| Exposed | 52/217 (24.0%) | 2.56 (1.59 to 4.10) | 2.27 (1.37 to 3.76) | 26/217 (12.0%) | 2.29 (1.23 to 4.28) | 1.89 (0.97 to 3.68) |
| Work category | ||||||
| Other than spinning or refining | 12/52 (23.1%) | 2.20 (1.05 to 4.63) | 2.02 (0.92 to 4.44) | 6/52 (11.5%) | 2.02 (0.70 to 5.09) | 1.89 (0.68 to 5.27) |
| Spinning or refining | 40/165 (24.2%) | 2.69 (1.62 to 4.46) | 2.36 (1.37 to 4.08) | 20/165 (12.1%) | 2.39 (1.23 to 4.66) | 1.89 (0.92 to 3.87) |
| Quartile by 6 year mean TTCA (1992–98) | ||||||
| L | 15/55 (27.3%) | 2.78 (1.38 to 5.62) | 2.63 (1.27 to 5.52) | 5/55 (9.1%) | 1.53 (0.54 to 4.31) | 1.29 (0.44 to 3.76) |
| ML | 17/55 (30.9%) | 3.52 (1.78 to 6.97) | 3.22 (1.56 to 6.63) | 9/55 (16.4%) | 3.22 (1.36 to 7.61) | 2.69 (1.06 to 6.81) |
| MH | 9/53 (17.0%) | 1.48 (0.66 to 3.32) | 1.19 (0.51 to 2.81) | 6/53 (11.3%) | 1.98 (0.75 to 5.26) | 1.64 (0.58 to 4.62) |
| H | 11/54 (20.4%) | 2.71 (1.24 to 5.92) | 2.28 (1.01 to 5.17) | 6/54 (11.1%) | 2.71 (1.00 to 7.36) | 2.15 (0.76 to 6.12) |
| Quartile by TTCA in 1992 | ||||||
| L′ | 11/55 (20.0%) | 1.95 (0.92 to 4.17) | 1.85 (0.83 to 4.12) | 5/55 (9.1%) | 1.64 (0.58 to 4.64) | 1.45 (0.49 to 4.27) |
| ML′ | 13/54 (24.1%) | 2.57 (1.24 to 5.36) | 2.10 (0.96 to 4.59) | 6/54 (11.1%) | 2.10 (0.79 to 5.58) | 1.56 (0.56 to 4.40) |
| MH′ | 16/54 (29.6%) | 3.36 (1.68 to 6.73) | 2.78 (1.34 to 5.75) | 11/54 (20.4%) | 4.31 (1.90 to 9.79) | 3.31 (1.38 to 7.94) |
| H′ | 12/54 (22.2%) | 2.44 (1.15 to 5.17) | 2.35 (1.07 to 5.16) | 4/54 (7.4%) | 1.39 (0.45 to 4.31) | 1.25 (0.38 to 4.07) |