Table 4

Age at baseline, exposure level, and incidence of retinal microaneurysm and ischaemic findings†

Exposure index‡Incidence
Exposure duration prior to the study (y)TTCA (mg/g creatinine)CS2 (ppm)Non-exposed workersCS2 exposed workers
†Defined as Minnesota codes I, IV1–3, V1–3 or receiving treatment for ischaemia.
‡Geometric mean (GSD).
*p<0.05 compared to the non-exposed workers by χ2 test or Fisher’s exact method.
Retinal microaneurysm
Entire group10.7 (2.3)1.5 (1.9)4.8 (1.8)11/219 (5.0%)17/184 (9.2%)
Age at baseline
    <356.1 (2.1)1.9 (2.0)6.0 (1.7)5/78 (6.4%)7/79 (8.9%)
    35–4416.0 (1.8)1.3 (1.9)4.0 (1.8)3/99 (3.0%)8/87 (9.2%)
    ⩾4519.4 (1.6)1.4 (1.9)4.1 (1.9)3/42 (7.1%)2/18 (11.1%)
Ischaemic findings
Entire group10.8 (2.3)1.6 (1.9)5.0 (1.8)21/329 (6.4%)30/254 (11.8%)*
Age at baseline
    <355.7 (2.1)1.9 (1.9)6.0 (1.7)5/131 (3.8%)13/105 (12.4%)*
    35–4416.5 (1.7)1.4 (1.9)4.3 (1.8)10/150 (6.7%)11/124 (8.9%)
    ⩾4520.1 (1.5)1.5 (1.9)4.7 (2.0)6/48 (12.5%)6/25 (24.0%)