Independent predictors of sensitisation to laboratory animal allergens in three different prognostic models
| Model 1 n = 280 | Model 2 n = 279 | Model 3 n = 280 | ||||
|---|---|---|---|---|---|---|
| β (SE) | OR (95% CI) | β (SE) | OR (95% CI) | β (SE) | OR (95% CI) | |
| β, regression coefficient, SE, standard error; OR, odds ratio; CI, confidence interval; AUC, area under the receiver operator characteristic curve. | ||||||
| Intercept | −3.24 (0.42) | – | −3.76 (0.48) | – | −3.24 (0.42) | – |
| Determinants from questionnaire | ||||||
| Employed ⩽4 years | 0.91 (0.41) | 2.5 (1.1 to 5.5) | 0.97 (0.43) | 2.2 (0.9 to 5.1) | 0.84 (0.42) | 2.3 (1.0 to 5.2) |
| Symptoms suggesting atopy | 0.58 (0.39) | 1.8 (0.8 to 3.8) | 0.17 (0.44) | 1.2 (0.5 to 2.8) | 0.28 (0.41) | 1.3 (0.6 to 3.0) |
| Work related allergic symptoms | 0.98 (0.51) | 2.7 (1.0 to 7.2) | 0.78 (0.56) | 2.2 (0.7 to 6.5 | 0.86 (0.52) | 2.4 (0.9 to 6.6) |
| Working ⩾12 hours with rats | 0.92 (0.42) | 2.5 (1.1 to 3.7) | 0.99 (0.44) | 2.7 (1.1 to 6.4) | 0.88 (0.43) | 2.4 (1.0 to 5.6) |
| Determinants from additional tests | ||||||
| Total IgE ⩾100 kU/l | Not used | – | 1.43 (0.46) | 4.2 (1.7 to 10.3) | Not used | – |
| Positive IgE to non-animal common allergens | Not used | – | 1.18 (0.45) | 3.3 (1.4 to 7.8) | Not used | – |
| Positive SPT to non-animal common allergens (tree or hdm or grass) | Not used | – | Not used | – | 1.39 (0.41) | 4.0 (1.8 to 8.9) |
| AUC (SD) | 0.73 (0.04) | 0.81 (0.04) | 0.78 (0.05) | |||
| 95% CI | 0.65 to 0.82 | 0.73 to 0.89 | 0.70 to 0.86 | |||