Odds ratios for animal exposures and wheeze by atopy and asthma status among farmers in the Agricultural Health Study
| Exposure prevalence | ||||||||
|---|---|---|---|---|---|---|---|---|
| Wheeze | No wheeze | p interaction‡ | ||||||
| Exposure Atopy/asthma status | n | % | n | % | Odds ratio† | 95% CI | Atopy | Asthma |
| †Odds ratios adjusted for age, state, smoking (past and current), atopy-asthma status, and asthma*current smoking. | ||||||||
| Referent group is those with same asthma-atopy status who did not participate in that activity. | ||||||||
| ‡p value for two way cross product interaction terms. If atopy*asthma*exposure interactions were present at p<0.25, two way interactions were not reported. | ||||||||
| §p value for atopy*asthma*dairy interaction term = 0.097. | ||||||||
| ¶p value for atopy*asthma*milk cows interaction term = 0.15. | ||||||||
| Animals | ||||||||
| Beef cattle | 0.02 | 0.34 | ||||||
| No atopy: no asthma | 1006 | 68 | 5760 | 90 | 1.03 | 0.94 to 1.12 | ||
| Atopy: no asthma | 205 | 14 | 524 | 8 | 1.29 | 1.04 to 1.60 | ||
| No atopy: asthma | 136 | 9 | 99 | 2 | 0.85 | 0.61 to 1.19 | ||
| Atopy: asthma | 127 | 9 | 47 | 1 | 1.25 | 0.82 to 1.92 | ||
| Dairy cattle | – | –§ | ||||||
| No atopy: no asthma | 162 | 70 | 822 | 91 | 1.28 | 1.04 to 1.48 | ||
| Atopy: no asthma | 26 | 11 | 63 | 7 | 1.19 | 0.74 to 1.92 | ||
| No atopy: asthma | 18 | 8 | 11 | 1 | 1.10 | 0.51 to 2.37 | ||
| Atopy: asthma | 25 | 11 | 3 | 0.3 | 3.84 | 1.14 to 12.98 | ||
| Hogs | 0.17 | 0.93 | ||||||
| No atopy: no asthma | 900 | 72 | 5172 | 92 | 1.09 | 0.99 to 1.20 | ||
| Atopy: no asthma | 149 | 12 | 366 | 6 | 1.34 | 1.06 to 1.69 | ||
| No atopy: asthma | 108 | 9 | 64 | 1 | 1.22 | 0.85 to 1.77 | ||
| Atopy: asthma | 99 | 8 | 40 | 1 | 1.14 | 0.73 to 1.78 | ||
| Sheep | 0.99 | 0.58 | ||||||
| No atopy: no asthma | 104 | 70 | 572 | 89 | 1.13 | 0.91 to 1.40 | ||
| Atopy: no asthma | 18 | 12 | 53 | 8 | 1.08 | 0.62 to 1.88 | ||
| No atopy: asthma | 15 | 10 | 12 | 2 | 0.87 | 0.40 to 1.40 | ||
| Atopy: asthma | 12 | 8 | 5 | 1 | 1.05 | 0.36 to 3.04 | ||
| Poultry | 0.05 | 0.5 | ||||||
| No atopy: no asthma | 124 | 66 | 517 | 90 | 1.29 | 1.05 to 1.58 | ||
| Atopy: no asthma | 30 | 16 | 43 | 7 | 2.02 | 1.24 to 3.28 | ||
| No atopy: asthma | 19 | 10 | 13 | 2 | 0.95 | 0.46 to 1.92 | ||
| Atopy: asthma | 15 | 8 | 3 | 1 | 2.03 | 0.58 to 7.18 | ||
| Eggs | 0.04 | 0.48 | ||||||
| No atopy: no asthma | 50 | 67 | 186 | 93 | 1.55 | 1.12 to 2.14 | ||
| Atopy: no asthma | 12 | 16 | 9 | 4 | 4.36 | 1.80 to 10.53 | ||
| No atopy: asthma | 9 | 12 | 5 | 2 | 1.20 | 0.39 to 3.65 | ||
| Atopy: asthma | 4 | 5 | 1 | 1 | 1.55 | 0.17 to 14.18 | ||
| Animal production activities | ||||||||
| Milk cows | – | –¶ | ||||||
| No atopy: no asthma | 163 | 69 | 810 | 91 | 1.26 | 1.05 to 1.50 | ||
| Atopy: no asthma | 31 | 13 | 73 | 8 | 1.24 | 0.79 to 1.93 | ||
| No atopy: asthma | 18 | 8 | 8 | 1 | 1.53 | 0.65 to 3.58 | ||
| Atopy: asthma | 24 | 10 | 2 | 0.2 | 5.51 | 1.28 to 23.72 | ||
| Veterinary procedures | 0.23 | 0.41 | ||||||
| No atopy: no asthma | 1422 | 70 | 7927 | 90 | 1.22 | 1.11 to 1.33 | ||
| Atopy: no asthma | 259 | 13 | 694 | 8 | 1.32 | 1.06 to 1.65 | ||
| No atopy: asthma | 171 | 8 | 120 | 1 | 0.95 | 0.67 to 1.36 | ||
| Atopy: asthma | 190 | 9 | 65 | 1 | 1.44 | 0.93 to 2.23 | ||
| Butcher animals | 0.36 | 0.37 | ||||||
| No atopy: no asthma | 418 | 69 | 1816 | 89 | 1.27 | 1.13 to 1.43 | ||
| Atopy: no asthma | 86 | 14 | 179 | 9 | 1.41 | 1.06 to 1.87 | ||
| No atopy: asthma | 51 | 8 | 24 | 1 | 1.40 | 0.83 to 2.35 | ||
| Atopy: asthma | 51 | 8 | 11 | 1 | 2.06 | 1.03 to 4.10 | ||
| Swine work | 0.88 | 0.41 | ||||||
| No atopy: no asthma | 794 | 72 | 4277 | 91 | 1.19 | 1.08 to 1.32 | ||
| Atopy: no asthma | 120 | 11 | 316 | 7 | 1.24 | 0.96 to 1.58 | ||
| No atopy: asthma | 98 | 9 | 49 | 1 | 1.55 | 1.04 to 2.29 | ||
| Atopy: asthma | 93 | 8 | 37 | 1 | 1.15 | 0.73 to 1.81 | ||
| Grind feed | 0.25 | 0.91 | ||||||
| No atopy: no asthma | 1217 | 71 | 6979 | 91 | 1.11 | 1.02 to 1.22 | ||
| Atopy: no asthma | 203 | 12 | 537 | 7 | 1.30 | 1.04 to 1.61 | ||
| No atopy: asthma | 153 | 9 | 93 | 1 | 1.21 | 0.86 to 1.69 | ||
| Atopy: asthma | 148 | 9 | 59 | 1 | 1.17 | 0.77 to 1.77 | ||
| Handle grain | 0.48 | 0.14 | ||||||
| No atopy: no asthma | 1840 | 69 | 10606 | 90 | 1.09 | 0.98 to 1.21 | ||
| Atopy: no asthma | 333 | 13 | 927 | 8 | 1.21 | 0.96 to 1.52 | ||
| No atopy: asthma | 258 | 10 | 156 | 1 | 1.45 | 1.01 to 2.08 | ||
| Atopy: asthma | 225 | 8 | 89 | 1 | 1.34 | 0.85 to 2.13 | ||