Comparison of urinary 8-OHdG, Cr, and creatinine concentrations for Cr workers and control group
| Variables | Cr workers (n=48) | Control group (n=19) | p value |
|---|---|---|---|
| *Mean±SD. | |||
| 8-OHdG (nM) (range) | 73.2±62.8* | 44.6±25.8 | <0.01 |
| (7.6–395.7) | (5.7–88.8) | ||
| Log 8-OHdG (nM) (range) | 38.9±3.2 | 36.9±3.3 | 0.03 |
| (29.9–47.1) | (28.3–40.9) | ||
| 8-OHdG (pmol/kg) (range) | 1149.5±759.5 | 730.2±377.6 | 0.02 |
| (153.1–4209.4) | (92.0–1479.6) | ||
| Log 8-OHdG (nM) (range) | 20.4±3.0 (12.1–27.2) | 18.4±3.2 (9.7–22.4) | 0.02 |
| 8-OHdG (pmol/cre. nM) (range) | 4.65±2.38 | 4.34±1.08 | 0.88 |
| (1.70–13.53) | (2.06–6.89) | ||
| Log 8-OHdG (pmol/cre. nM) (range) | 27.10±2.15 | 27.16±1.17 | 0.91 |
| (23.06–32.43) | (23.93–29.38) | ||
| Urinary Cr (μg/l) (range) | 12.81±23.29 | 0.99±0.75 | 0.03 |
| (0.20–144.0) | (0.20–3.00) | <0.01 | |
| Log urinary Cr (μg/l) | 1.51±1.51 | −0.26±0.72 | |
| Urinary Cr (μg/g cre.) (range) | 5.72±7.65 | 1.21±1.16 | 0.01 |
| (0.02–39.28) | (0.15–4.62) | <0.01 | |
| Log urinary Cr | 0.88±1.59 | −0.23±0.96 | |
| Creatinine (mg/dl) (range) | 182.9±97.3 | 123.9±71.2 | 0.017 |
| (33.8–400.4) | (18.2–273.0) | ||