Frequencies and adjusted odds ratios (OR) with 95% confidence intervals (CI) of abnormal serum aminotransferase activity stratified by exposure classification and hepatitis virus infection; all odds ratios were adjusted for age, body mass index, and alcohol drinking
| Category | AST (n=58) | ALT (n=103) | ||||
|---|---|---|---|---|---|---|
| % | OR (95% CI)† | OR (95% CI)‡ | % | OR (95% CI)† | OR (95% CI)‡ | |
| *p<0.01 by Mantel-Haenszel χ2 test for trend analysis. | ||||||
| †The referent group (OR=1) refers to workers with low chemical exposure and negative hepatitis virus infection. | ||||||
| ‡The referent group (OR=1) refers to workers with low chemical exposure and positive hepatitis virus infection. | ||||||
| HBsAg (+) or anti-HCV (+) | ||||||
| High exposure | 56.3 | 10.6 (3.6 to 31.5)* | 6.2 (1.8 to 21.4)* | 62.5 | 6.4 (2.1 to 19.1)* | 6.5 (1.8 to 23.6)* |
| Moderate exposure | 23.5 | 3.0 (1.1 to 8.0) | 1.6 (0.4 to 5.7) | 35.3 | 2.1 (0.9 to 5.0) | 2.3 (0.7 to 7.5) |
| Low exposure | 15.9 | 2.3 (0.9 to 5.4) | 1.0 (referent) | 19.0 | 1.4 (0.7 to 3.0) | 1.0 (referent) |
| HBsAg (−) and anti-HCV (−) | ||||||
| High exposure | 1.7 | 0.5 (0.1 to 1.5) | 11.7 | 0.5 (0.2 to 1.3) | ||
| Moderate exposure | 5.7 | 0.6 (0.3 to 1.6) | 14.6 | 0.7 (0.4 to 1.3) | ||
| Low exposure | 8.8 | 1.0 (referent) | 16.4 | 1.0 (referent) | ||