Demographic data
|
n=215
|
n=110
|
n=50
|
n=39
|
Age (y), mean (SD) | 46.1 (11.5) | 38.3 (10.7) | 44.6 (10.0) | 36.7 (9.2) |
Male, n (%) | 121 (56.3) | 51 (46.4) | 32 (64.0) | 20 (51.3) |
Female, n (%) | 94 (43.7) | 59 (53.6) | 18 (36.0) | 19 (48.7) |
Smoking status, n (%) |
Current smokers | 24 (11.2) | 30 (27.3) | 14 (28.0) | 9 (23.1) |
Ex-smokers | 29 (13.5) | 21 (19.1) | 3 (6.0) | 5 (12.8) |
Non-smokers | 162 (75.3) | 59 (53.6) | 33 (66.0) | 25 (64.1) |
Pack-years, mean (SD) | 16.4 (14.9) | 8.6 (9.4) | 21.3 (15.7) | 11.7 (15.9) |
Altitude, n (%) |
Plain | 97 (45.1) | 48 (43.6) | 28 (56.0) | 17 (43.6) |
Tableland | 118 (54.9) | 62 (56.4) | 22 (44.0) | 22 (56.4) |
Symptoms, n (%)
|
n=214
|
n=110
|
n=50
|
n=39
|
Asthma | 12 (5.6) | 4 (3.6) | 4 (8.0) | 1 (2.6) |
Wheezing, LY | 12 (5.6) | 0 | 3 (6.0) | 2 (5.1) |
Wheezing with breathlessness, LY | 9 (4.2) | 0 | 2 (4.0) | 2 (5.1) |
Wheezing apart from a cold, LY* | 7 (3.3) | 0 | 4 (8.0) | 2 (5.1) |
Usual morning cough | 24 (11.2) | 4 (3.6) | 9 (18.0) | 2 (5.1) |
Usual morning phlegm | 27 (12.6) | 2 (1.8) | 9 (18.0) | 1 (2.6) |
Chronic bronchitis | 14 (6.5) | 1 (0.9) | 6 (12.0) | 0 |
Dyspnoea | 43 (20.1) | 12 (10.9) | 6 (12.0) | 7 (17.9) |
Respiratory function, mean (SD)
|
n=198
|
n=106
|
n=47
|
n=38
|
% VC | 102.7 (14.2) | 99.7 (13.0) | 101.0 (14.8) | 102.3 (13.5) |
% FEV1 | 99.3 (14.9) | 98.0 (13.7) | 95.1 (11.6) | 98.4 (15.6) |
% FEV1/VC | 96.3 (8.7) | 99.7 (16.6) | 95.0 (10.5) | 96.2 (11.3) |
% FEF25–75 | 85.8 (24.0) | 87.2 (27.2) | 79.8 (20.8) | 85.3 (23.8) |
Immunological tests
|
n=212
|
n=102
|
n=49
|
n=39
|
Total IgE, mean (SD) | 102.6 (468.3) | 69.1 (10.0) | 204.9 (459.5) | 56.8 (81.2) |
Phadiatop +, n (%) | 30 (14.2) | 20 (19.4) | 11 (22.4) | 7 (17.9) |
Skin prick tests +, n (%) | 78 (36.8) | 43 (40.2) | 16 (32) | 15 (39.5) |